Human umbilical cord blood-derived mesenchymal stem cells prevent diabetic renal injury through paracrine action

JH Park, I Hwang, SH Hwang, H Han, H Ha - Diabetes research and clinical …, 2012 - Elsevier
AIMS: The present study examined renoprotective effect of human umbilical cord blood-
derived mesenchymal stem cells (hUCB-MSC) in diabetes. NRK-52E cells were utilized to …

Evaluation of intrarenal mesenchymal stem cell injection for treatment of chronic kidney disease in cats: a pilot study

JM Quimby, TL Webb, DS Gibbons… - Journal of feline …, 2011 - journals.sagepub.com
The feasibility of autologous intrarenal mesenchymal stem cell (MSC) therapy in cats with
chronic kidney disease (CKD) was investigated. Six cats (two healthy, four with CKD) …

Systematic review and meta‐analysis of mesenchymal stem/stromal cells therapy for impaired renal function in small animal models

Y Wang, J He, X Pei, W Zhao - Nephrology, 2013 - Wiley Online Library
Aim The meta‐analysis of recent small animal experiments of mesenchymal stem/stromal
cells (MSC) therapy for impaired kidney could provide significant clues to design large …

Mesenchymal Stem/Stromal Cell–Derived Extracellular Vesicles for Chronic Kidney Disease: Are We There Yet?

A Eirin, LO Lerman - Hypertension, 2021 - Am Heart Assoc
Mesenchymal stem/stromal cells (MSCs) are the most utilized cell type for cellular therapy,
partly due to their important proliferative potential and ability to differentiate into various cell …

Selective intrarenal delivery of mesenchymal stem cell-derived extracellular vesicles attenuates myocardial injury in experimental metabolic renovascular disease

L Zhang, XY Zhu, Y Zhao, A Eirin, L Liu… - Basic Research in …, 2020 - Springer
Extracellular vesicles (EVs) deliver genes and proteins to recipient cells, and mediate
paracrine actions of their parent cells. Intrarenal delivery of mesenchymal stem cell (MSC) …

Targeting endogenous repair pathways after AKI

BD Humphreys, V Cantaluppi, D Portilla… - Journal of the …, 2016 - journals.lww.com
AKI remains a highly prevalent disease associated with poor short–and long–term outcomes
and high costs. Although significant advances in our understanding of repair after AKI have …

Mesenchymal stem cells from rats with chronic kidney disease exhibit premature senescence and loss of regenerative potential

BM Klinkhammer, R Kramann, M Mallau, A Makowska… - PloS one, 2014 - journals.plos.org
Mesenchymal stem cell (MSC) transplantation has the potential for organ repair.
Nevertheless, some factors might lessen the regenerative potential of MSCs, eg donor age …

Bottlenecks in the efficient use of advanced therapy medicinal products based on mesenchymal stromal cells

N Escacena, E Quesada-Hernández… - Stem cells …, 2015 - Wiley Online Library
Mesenchymal stromal cells (MSCs) have been established as promising candidate sources
of universal donor cells for cell therapy due to their contributions to tissue and organ …

Mesenchymal stem cell-derived exosomes: versatile nanomaterials for skin wound treatment

Y Xiao, H Li, J Zhang, S Yang, C Zhang, Y Huang… - Nano Research, 2024 - Springer
Accumulating studies reveal that mesenchymal stem cells (MSCs) promote skin wound
healing mainly through the paracrine effects. Exosomes, one of the crucial paracrine …

Transplantation of bone marrow-derived MSCs improves cisplatinum-induced renal injury through paracrine mechanisms

K Cheng, P Rai, A Plagov, X Lan, D Kumar… - … and molecular pathology, 2013 - Elsevier
Mesenchymal stem cells (MSCs) have been reported to preserve renal function in various
models of acute kidney injury (AKI). Different routes were used to transplant MSCs but the …