[HTML][HTML] The Challenge of overcoming antibiotic resistance in carbapenem-resistant Gram-negative bacteria:“Attack on Titan”
G Mancuso, S De Gaetano, A Midiri, S Zummo… - Microorganisms, 2023 - mdpi.com
The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …
[HTML][HTML] Tackling Carbapenem Resistance and the Imperative for One Health Strategies—Insights from the Portuguese Perspective
I Mó, GJ da Silva - Antibiotics, 2024 - mdpi.com
Carbapenemases, a class of enzymes specialized in the hydrolysis of carbapenems,
represent a significant threat to global public health. These enzymes are classified into …
represent a significant threat to global public health. These enzymes are classified into …
Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-β-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding
YH Yan, TT Zhang, R Li, SY Wang, LL Wei… - Journal of Medicinal …, 2023 - ACS Publications
Metallo-β-lactamases (MBLs) are zinc-dependent enzymes capable of hydrolyzing all
bicyclic β-lactam antibiotics, posing a great threat to public health. However, there are …
bicyclic β-lactam antibiotics, posing a great threat to public health. However, there are …
[HTML][HTML] Clonal distribution and its association with the carbapenem resistance mechanisms of carbapenem-non-susceptible Pseudomonas aeruginosa isolates from …
N Kim, SY Ko, SY Park, SY Kim, KT Kwon… - Annals of Laboratory …, 2024 - ncbi.nlm.nih.gov
Background Carbapenem resistance in Pseudomonas aeruginosa is a serious global health
problem. We investigated the clonal distribution and its association with the carbapenem …
problem. We investigated the clonal distribution and its association with the carbapenem …
In vitro activity of cefiderocol against European Pseudomonas aeruginosa and Acinetobacter spp., including isolates resistant to meropenem and recent β-lactam/β …
A Santerre Henriksen, K Jeannot, A Oliver… - Microbiology …, 2024 - Am Soc Microbiol
Carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter spp. represent major
threats and have few approved therapeutic options. Non-fermenting Gram-negative isolates …
threats and have few approved therapeutic options. Non-fermenting Gram-negative isolates …
[HTML][HTML] The Prevalence of Metallo-Beta-Lactamese-(MβL)-Producing Pseudomonas aeruginosa Isolates in Brazil: A Systematic Review and Meta-Analysis
PAS Dos Santos, MJA Silva, MIM Gouveia, LNGC Lima… - Microorganisms, 2023 - mdpi.com
The purpose of the current study is to describe the prevalence of Pseudomonas aeruginosa
(PA)-producing MβL among Brazilian isolates and the frequency of bla SPM-1 in MβL-PA …
(PA)-producing MβL among Brazilian isolates and the frequency of bla SPM-1 in MβL-PA …
[HTML][HTML] Veratryl Alcohol Attenuates the Virulence and Pathogenicity of Pseudomonas aeruginosa Mainly via Targeting las Quorum-Sensing System
S Fu, W Song, X Han, L Chen, L Shen - Microorganisms, 2024 - mdpi.com
Pseudomonas aeruginosa is an opportunistic pathogen that usually causes chronic
infections and even death in patients. The treatment of P. aeruginosa infection has become …
infections and even death in patients. The treatment of P. aeruginosa infection has become …
[HTML][HTML] Fate of horizontal-gene-transfer markers and beta-lactamase genes during thermophilic composting of human excreta
KA Werner, L Feyen, T Hübner, N Brüggemann, K Prost… - Microorganisms, 2023 - mdpi.com
Thermophilic composting is a suitable treatment for the recycling of organic wastes for
agriculture. However, using human excreta as feedstock for composting raises concerns …
agriculture. However, using human excreta as feedstock for composting raises concerns …
Emergence of carbapenem-resistant Pseudomonas aeruginosa ST179 producing both IMP-16 and KPC-2: a case study of introduction from Peru to Spain
We describe four cases of a novel carbapenem-resistant Pseudomonas aeruginosa ST179
clone carrying the bla KPC-2 or bla KPC-35 gene together with bla IMP-16, imported from …
clone carrying the bla KPC-2 or bla KPC-35 gene together with bla IMP-16, imported from …
[HTML][HTML] In Silico Molecular Analysis of Carbapenemase-Negative Carbapenem-Resistant Pseudomonas aeruginosa Strains in Greece
K Tsilipounidaki, CG Gkountinoudis, Z Florou… - Microorganisms, 2024 - mdpi.com
To date, three carbapenem resistance mechanisms have been identified: carbapenemase
released from the pathogen, changes in the expression of the outer membrane OprD porin …
released from the pathogen, changes in the expression of the outer membrane OprD porin …