Immune-checkpoint inhibitors: long-term implications of toxicity
The development of immune-checkpoint inhibitors (ICIs) has heralded a new era in cancer
treatment, enabling the possibility of long-term survival in patients with metastatic disease …
treatment, enabling the possibility of long-term survival in patients with metastatic disease …
Risk factors and biomarkers for immune-related adverse events: a practical guide to identifying high-risk patients and rechallenging immune checkpoint inhibitors
A Chennamadhavuni, L Abushahin, N Jin… - Frontiers in …, 2022 - frontiersin.org
Immune-related adverse events (irAEs) are a range of complications associated with the use
of immune-checkpoint inhibitors (ICIs). Two major classes of ICIs widely used are Cytotoxic …
of immune-checkpoint inhibitors (ICIs). Two major classes of ICIs widely used are Cytotoxic …
[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events
JR Brahmer, H Abu-Sbeih, PA Ascierto… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several
cancers. While these immunotherapies have improved patient outcomes in many clinical …
cancers. While these immunotherapies have improved patient outcomes in many clinical …
[HTML][HTML] Acute kidney injury in patients treated with immune checkpoint inhibitors
Background Immune checkpoint inhibitor-associated acute kidney injury (ICPi-AKI) has
emerged as an important toxicity among patients with cancer. Methods We collected data on …
emerged as an important toxicity among patients with cancer. Methods We collected data on …
The mechanism of drug nephrotoxicity and the methods for preventing kidney damage
E Kwiatkowska, L Domański, V Dziedziejko… - International Journal of …, 2021 - mdpi.com
Acute kidney injury (AKI) is a global health challenge of vast proportions, as approx. 13.3%
of people worldwide are affected annually. The pathophysiology of AKI is very complex, but …
of people worldwide are affected annually. The pathophysiology of AKI is very complex, but …
The use of immune checkpoint inhibitors in oncology and the occurrence of AKI: where do we stand?
Immune checkpoint inhibitors (ICIs) are a novel class of immunotherapy drugs that have
improved the treatment of a broad spectrum of cancers as metastatic melanoma, non-small …
improved the treatment of a broad spectrum of cancers as metastatic melanoma, non-small …
Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆
Adverse events (AEs) related to the use of immune checkpoint inhibitor (ICI) therapy are
defined as immune-related (IR) AEs (irAEs). irAEs are graded according to the Common …
defined as immune-related (IR) AEs (irAEs). irAEs are graded according to the Common …
Onconephrology: the intersections between the kidney and cancer
MH Rosner, KD Jhaveri, BA McMahon… - CA: a cancer journal …, 2021 - Wiley Online Library
Onconephrology is a new subspecialty of nephrology that recognizes the important
intersections of kidney disease with cancer. This intersection takes many forms and includes …
intersections of kidney disease with cancer. This intersection takes many forms and includes …
A multi-center study on safety and efficacy of immune checkpoint inhibitors in cancer patients with kidney transplant
N Murakami, P Mulvaney, M Danesh, A Abudayyeh… - Kidney international, 2021 - Elsevier
Immune checkpoint inhibitors (ICIs) are widely used for various malignancies. However,
their safety and efficacy in patients with a kidney transplant have not been defined. To …
their safety and efficacy in patients with a kidney transplant have not been defined. To …
[HTML][HTML] A systematic review of immune checkpoint inhibitor–associated glomerular disease
A Kitchlu, KD Jhaveri, S Wadhwani… - Kidney international …, 2021 - Elsevier
Introduction Immune checkpoint inhibitors (ICIs) are increasingly used to treat cancers.
Kidney immune-related adverse events (IRAEs) are now well recognized, with the incidence …
Kidney immune-related adverse events (IRAEs) are now well recognized, with the incidence …