SARS-CoV-2 and the spike protein in endotheliopathy

L Perico, A Benigni, G Remuzzi - Trends in Microbiology, 2024 - cell.com
Abstract SARS-CoV-2, the causative agent of COVID-19, primarily affects the epithelial
compartment in the upper and lower airways. There is evidence that the microvasculature in …

Interaction of SARS-CoV-2 with host cells and antibodies: experiment and simulation

H Nguyen, HL Nguyen, PD Lan, NQ Thai… - Chemical Society …, 2023 - pubs.rsc.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …

Diabetes mellitus, energy metabolism, and COVID-19

C Conte, E Cipponeri, M Roden - Endocrine Reviews, 2024 - academic.oup.com
Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …

Emerging roles of SARS-CoV-2 Spike-ACE2 in immune evasion and pathogenesis

CT Baldari, A Onnis, E Andreano, G Del Giudice… - Trends in …, 2023 - cell.com
The COVID-19 pandemic, caused by SARS-CoV-2, has caused an estimated 5 billion
infections and 20 million deaths by respiratory failure. In addition to the respiratory disease …

Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

K Wang, M Khoramjoo, K Srinivasan, PMK Gordon… - Cell Reports …, 2023 - cell.com
The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often
associated with debilitating symptoms and adverse multisystem consequences. We obtain …

DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner

MS Strine, WL Cai, J Wei, MM Alfajaro, RB Filler… - PLoS …, 2023 - journals.plos.org
Identifying host genes essential for Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) has the potential to reveal novel drug targets and further our understanding …

Aptamer-based diagnostic and therapeutic approaches for animal viruses: A review

Z Chen, Q Sun, Y Yang, X Nie, W Xiang, Y Ren… - International Journal of …, 2023 - Elsevier
Animal diseases often have significant consequences due to the unclear and time-
consuming diagnosis process. Furthermore, the emergence of new viral infections and drug …

[HTML][HTML] The potential role of ferroptosis in COVID-19-related cardiovascular injury

L Yang, Y Wu, W Jin, N Mo, G Ye, Z Su, L Tang… - Biomedicine & …, 2023 - Elsevier
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
emerged as a global health threat in 2019. An important feature of the disease is that …

Cardiovascular disease as part of Long COVID: a systematic review

V Tsampasian, M Bäck, M Bernardi… - European journal of …, 2024 - academic.oup.com
Aims Long COVID syndrome has had a major impact on million patients' lives worldwide.
The cardiovascular system is an important aspect of this multifaceted disease that may …

Discovery of highly potent covalent SARS-CoV-2 3CLpro inhibitors bearing 2-sulfoxyl-1, 3, 4-oxadiazole scaffold for combating COVID-19

FM Zhang, T Huang, F Wang, GS Zhang, D Liu… - European Journal of …, 2023 - Elsevier
Abstract The coronavirus disease (COVID-19) pandemic, caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged as a major public health …