How cancer hijacks the body's homeostasis through the neuroendocrine system
During oncogenesis, cancer not only escapes the body's regulatory mechanisms, but also
gains the ability to affect local and systemic homeostasis. Specifically, tumors produce …
gains the ability to affect local and systemic homeostasis. Specifically, tumors produce …
[HTML][HTML] Cholinergic system and its therapeutic importance in inflammation and autoimmunity
N Halder, G Lal - Frontiers in immunology, 2021 - frontiersin.org
Neurological and immunological signals constitute an extensive regulatory network in our
body that maintains physiology and homeostasis. The cholinergic system plays a significant …
body that maintains physiology and homeostasis. The cholinergic system plays a significant …
[HTML][HTML] Smart probes for optical imaging of T cells and screening of anti-cancer immunotherapies
M Bertolini, MS Wong, L Mendive-Tapia… - Chemical Society …, 2023 - pubs.rsc.org
T cells are an essential part of the immune system with crucial roles in adaptive response
and the maintenance of tissue homeostasis. Depending on their microenvironment, T cells …
and the maintenance of tissue homeostasis. Depending on their microenvironment, T cells …
[HTML][HTML] Immune regulation through tryptophan metabolism
SK Seo, B Kwon - Experimental & Molecular Medicine, 2023 - nature.com
Amino acids are fundamental units of molecular components that are essential for sustaining
life; however, their metabolism is closely interconnected to the control systems of cell …
life; however, their metabolism is closely interconnected to the control systems of cell …
[HTML][HTML] Breast cancer and neurotransmitters: emerging insights on mechanisms and therapeutic directions
P Jayachandran, F Battaglin, C Strelez, A Lenz… - Oncogene, 2023 - nature.com
Exploring the relationship between various neurotransmitters and breast cancer cell growth
has revealed their likely centrality to improving breast cancer treatment. Neurotransmitters …
has revealed their likely centrality to improving breast cancer treatment. Neurotransmitters …
[HTML][HTML] DNA damage and activation of cGAS/STING pathway induce tumor microenvironment remodeling
R Shen, D Liu, X Wang, Z Guo, H Sun… - Frontiers in cell and …, 2022 - frontiersin.org
DNA damage occurs throughout tumorigenesis and development. The immunogenicity of
DNA makes it an immune stimulatory molecule that initiates strong inflammatory responses …
DNA makes it an immune stimulatory molecule that initiates strong inflammatory responses …
[HTML][HTML] Role of adrenergic receptor signalling in neuroimmune communication
S Chhatar, G Lal - Current Research in Immunology, 2021 - Elsevier
Neuroimmune communication plays a crucial role in maintaining homeostasis and promptly
responding to any foreign insults. Sympathetic nerve fibres are innervated into all the …
responding to any foreign insults. Sympathetic nerve fibres are innervated into all the …
By what molecular mechanisms do social determinants impact cardiometabolic risk?
While it is well known from numerous epidemiologic investigations that social determinants
(socioeconomic, environmental, and psychosocial factors exposed to over the life-course) …
(socioeconomic, environmental, and psychosocial factors exposed to over the life-course) …
[HTML][HTML] Glucocorticoid hormones as modulators of the kynurenine pathway in chronic pain conditions
The pathogenesis of chronic pain entails a series of complex interactions among the
nervous, immune, and endocrine systems. Defined as pain lasting or recurring for more than …
nervous, immune, and endocrine systems. Defined as pain lasting or recurring for more than …
[HTML][HTML] Turicibacter fermentation enhances the inhibitory effects of Antrodia camphorata supplementation on tumorigenic serotonin and Wnt pathways and promotes …
Introduction: Diet-induced obesity has been shown to decrease the abundance of
Turicibacter, a genus known to play a role in the serotonin signaling system, which is …
Turicibacter, a genus known to play a role in the serotonin signaling system, which is …