How cancer hijacks the body's homeostasis through the neuroendocrine system

RM Slominski, C Raman, JY Chen, AT Slominski - Trends in neurosciences, 2023 - cell.com
During oncogenesis, cancer not only escapes the body's regulatory mechanisms, but also
gains the ability to affect local and systemic homeostasis. Specifically, tumors produce …

[HTML][HTML] Cholinergic system and its therapeutic importance in inflammation and autoimmunity

N Halder, G Lal - Frontiers in immunology, 2021 - frontiersin.org
Neurological and immunological signals constitute an extensive regulatory network in our
body that maintains physiology and homeostasis. The cholinergic system plays a significant …

[HTML][HTML] Smart probes for optical imaging of T cells and screening of anti-cancer immunotherapies

M Bertolini, MS Wong, L Mendive-Tapia… - Chemical Society …, 2023 - pubs.rsc.org
T cells are an essential part of the immune system with crucial roles in adaptive response
and the maintenance of tissue homeostasis. Depending on their microenvironment, T cells …

[HTML][HTML] Immune regulation through tryptophan metabolism

SK Seo, B Kwon - Experimental & Molecular Medicine, 2023 - nature.com
Amino acids are fundamental units of molecular components that are essential for sustaining
life; however, their metabolism is closely interconnected to the control systems of cell …

[HTML][HTML] Breast cancer and neurotransmitters: emerging insights on mechanisms and therapeutic directions

P Jayachandran, F Battaglin, C Strelez, A Lenz… - Oncogene, 2023 - nature.com
Exploring the relationship between various neurotransmitters and breast cancer cell growth
has revealed their likely centrality to improving breast cancer treatment. Neurotransmitters …

[HTML][HTML] DNA damage and activation of cGAS/STING pathway induce tumor microenvironment remodeling

R Shen, D Liu, X Wang, Z Guo, H Sun… - Frontiers in cell and …, 2022 - frontiersin.org
DNA damage occurs throughout tumorigenesis and development. The immunogenicity of
DNA makes it an immune stimulatory molecule that initiates strong inflammatory responses …

[HTML][HTML] Role of adrenergic receptor signalling in neuroimmune communication

S Chhatar, G Lal - Current Research in Immunology, 2021 - Elsevier
Neuroimmune communication plays a crucial role in maintaining homeostasis and promptly
responding to any foreign insults. Sympathetic nerve fibres are innervated into all the …

By what molecular mechanisms do social determinants impact cardiometabolic risk?

Y Baumer, MA Pita, AS Baez… - Clinical …, 2023 - portlandpress.com
While it is well known from numerous epidemiologic investigations that social determinants
(socioeconomic, environmental, and psychosocial factors exposed to over the life-course) …

[HTML][HTML] Glucocorticoid hormones as modulators of the kynurenine pathway in chronic pain conditions

F Jovanovic, V Jovanovic, NN Knezevic - Cells, 2023 - mdpi.com
The pathogenesis of chronic pain entails a series of complex interactions among the
nervous, immune, and endocrine systems. Defined as pain lasting or recurring for more than …

[HTML][HTML] Turicibacter fermentation enhances the inhibitory effects of Antrodia camphorata supplementation on tumorigenic serotonin and Wnt pathways and promotes …

TC Lin, A Soorneedi, Y Guan, Y Tang, E Shi… - Frontiers in …, 2023 - frontiersin.org
Introduction: Diet-induced obesity has been shown to decrease the abundance of
Turicibacter, a genus known to play a role in the serotonin signaling system, which is …