[HTML][HTML] Engineering microneedle patches for improved penetration: analysis, skin models and factors affecting needle insertion

P Makvandi, M Kirkby, ARJ Hutton, M Shabani… - Nano-Micro Letters, 2021 - Springer
Transdermal microneedle (MN) patches are a promising tool used to transport a wide variety
of active compounds into the skin. To serve as a substitute for common hypodermic needles …

[HTML][HTML] Functional surface microstructures inspired by nature–From adhesion and wetting principles to sustainable new devices

E Arzt, H Quan, RM McMeeking, R Hensel - Progress in Materials Science, 2021 - Elsevier
In the course of evolution nature has arrived at startling materials solutions to ensure
survival. Investigations into biological surfaces, ranging from plants, insects and geckos to …

Modeling and simulation in tribology across scales: An overview

AI Vakis, VA Yastrebov, J Scheibert, L Nicola, D Dini… - Tribology …, 2018 - Elsevier
This review summarizes recent advances in the area of tribology based on the outcome of a
Lorentz Center workshop surveying various physical, chemical and mechanical phenomena …

The mechanical behavior of skin: Structures and models for the finite element analysis

JM Benítez, FJ Montáns - Computers & Structures, 2017 - Elsevier
Soft biological tissues are complex materials with a large structural variety, with differences
in behavior, but with some common characteristics. Skin is an archetypal soft tissue which …

Mathematical and computational modelling of skin biophysics: a review

G Limbert - Proceedings of the Royal Society A …, 2017 - royalsocietypublishing.org
The objective of this paper is to provide a review on some aspects of the mathematical and
computational modelling of skin biophysics, with special focus on constitutive theories based …

Engineering and development of a tissue model for the evaluation of microneedle penetration ability, drug diffusion, photothermal activity, and ultrasound imaging: a …

P Makvandi, M Shabani, N Rabiee… - Advanced …, 2023 - Wiley Online Library
Driven by regulatory authorities and the ever‐growing demands from industry, various
artificial tissue models have been developed. Nevertheless, there is no model to date that is …

Thermal‐disrupting interface mitigates intercellular cohesion loss for accurate topical antibacterial therapy

B Hu, C Berkey, T Feliciano, X Chen, Z Li… - Advanced …, 2020 - Wiley Online Library
Bacterial infections remain a leading threat to global health because of the misuse of
antibiotics and the rise in drug‐resistant pathogens. Although several strategies such as …

Microneedle arrays for drug delivery and diagnostics: toward an optimized design, reliable insertion, and penetration

V Ebrahiminejad, PD Prewett… - Advanced Materials …, 2022 - Wiley Online Library
In the past two decades, microneedles have been extensively studied for transdermal
delivery of drug or vaccines and for bio‐fluid extraction. Microneedle‐based devices consist …

[HTML][HTML] Wearable skin sensors and their challenges: A review of transdermal, optical, and mechanical sensors

A Ahmad Tarar, U Mohammad, S K. Srivastava - Biosensors, 2020 - mdpi.com
Wearable technology and mobile healthcare systems are both increasingly popular
solutions to traditional healthcare due to their ease of implementation and cost-effectiveness …

[HTML][HTML] Finite element analysis of the amputated lower limb: A systematic review and recommendations

AS Dickinson, JW Steer, PR Worsley - Medical engineering & physics, 2017 - Elsevier
The care and rehabilitation of individuals after lower limb amputation presents a substantial
and growing socioeconomic challenge. Clinical outcome is closely linked to successful …