Methylmalonyl-CoA mutase is a key enzyme in intermediary metabolism, and children
deficient in enzyme activity have severe metabolic acidosis. We found that nitric oxide (NO) …

The objective of the present study was to delineate the molecular mechanisms for
mitochondrial contribution to oxidative stress induced by hypoxia and reoxygenation in the …

Diabetes mellitus (DM) is associated with increased production of reactive oxygen and
nitrogen species; consequently, an increase in lipid peroxidation and a decrease in …

Since the nineteenth century, when engineers were using nitroglycerin to blow up rockbeds,
and doctors were prescribing it to relieve angina, scientists have been exploring the …

Introduction 3. nNOS translocation to mitochondria: the mtNOS 4. Adaptation to O2 levels 5.
Adaptation to environment 6. Endocrine regulation 7. mtNOS modulation in development 8 …

The present study analyzed iNOS and eNOS mRNA expression and NO production during
development of hepatic abscess caused by Entamoeba histolytica trophozoites. One 374-bp …

Heart mitochondria play a central role in cell energy provision and in signaling. Nitric oxide
(NO) is a free radical which exerts an integral regulation of the cardiovascular system not …

Nitric oxide (NO•) plays an important role in various physiological processes. The aim of the
present study was to investigate if brain mitochondrial nitric oxide synthase (mtNOS) is …

Heart mitochondria are the major source of reactive oxygen and nitrogen species and play a
central role in cell energy provision and signaling. The NO produced by cardiac mtNOS is …

El óxido nítrico participa en funciones fisiológicas y fisiopatológicas, así como en el
mecanismo de defensa del sistema inmunológico de mamíferos contra parásitos, virus y …