ROS-triggered endothelial cell death mechanisms: Focus on pyroptosis, parthanatos, and ferroptosis

D Zheng, J Liu, H Piao, Z Zhu, R Wei, K Liu - Frontiers in immunology, 2022 - frontiersin.org
The endothelium is a single layer of epithelium covering the surface of the vascular system,
and it represents a physical barrier between the blood and vessel wall that plays an …

ROS generation and antioxidant defense systems in normal and malignant cells

AV Snezhkina, AV Kudryavtseva… - Oxidative medicine …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …

[HTML][HTML] Current mechanistic concepts in ischemia and reperfusion injury

MY Wu, GT Yiang, WT Liao, APY Tsai… - Cellular Physiology and …, 2018 - karger.com
Ischemia-reperfusion injury is associated with serious clinical manifestations, including
myocardial hibernation, acute heart failure, cerebral dysfunction, gastrointestinal …

The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors

N Liu, H Xu, Q Sun, X Yu, W Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …

Measurement and clinical significance of biomarkers of oxidative stress in humans

I Marrocco, F Altieri, I Peluso - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Oxidative stress is the result of the imbalance between reactive oxygen species (ROS)
formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are …

[HTML][HTML] The role of oxidative stress in neurodegenerative diseases

GH Kim, JE Kim, SJ Rhie, S Yoon - Experimental neurobiology, 2015 - ncbi.nlm.nih.gov
Oxidative stress is induced by an imbalanced redox states, involving either excessive
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …

[HTML][HTML] Reperfusion injury and reactive oxygen species: The evolution of a concept

DN Granger, PR Kvietys - Redox biology, 2015 - Elsevier
Reperfusion injury, the paradoxical tissue response that is manifested by blood flow-
deprived and oxygen-starved organs following the restoration of blood flow and tissue …

Oxidative stress in aging human skin

M Rinnerthaler, J Bischof, MK Streubel, A Trost… - Biomolecules, 2015 - mdpi.com
Oxidative stress in skin plays a major role in the aging process. This is true for intrinsic aging
and even more for extrinsic aging. Although the results are quite different in dermis and …

Oxidative stress: major threat in traumatic brain injury

N Khatri, M Thakur, V Pareek, S Kumar… - CNS & Neurological …, 2018 - ingentaconnect.com
Background & Objective: Traumatic Brain Injury (TBI) is one of the major causes of mortality
and morbidity worldwide. It represents mild, moderate and severe effects of physical assault …

Antioxidant peptides, the guardian of life from oxidative stress

Y Zhu, K Wang, X Jia, C Fu, H Yu… - Medicinal Research …, 2024 - Wiley Online Library
Reactive oxygen species (ROS) are produced during oxidative metabolism in aerobic
organisms. Under normal conditions, ROS production and elimination are in a relatively …