[HTML][HTML] Acute heart failure

M Arrigo, M Jessup, W Mullens, N Reza… - Nature Reviews …, 2020 - nature.com
Acute heart failure (AHF) is a syndrome defined as the new onset (de novo heart failure
(HF)) or worsening (acutely decompensated heart failure (ADHF)) of symptoms and signs of …

[HTML][HTML] Pathophysiology of obesity and its associated diseases

X Jin, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023 - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

Neurohormonal activation in heart failure with reduced ejection fraction

J Hartupee, DL Mann - Nature Reviews Cardiology, 2017 - nature.com
Heart failure with reduced ejection fraction (HFrEF) develops when cardiac output falls as a
result of cardiac injury. The most well-recognized of the compensatory homeostatic …

Heart failure and kidney dysfunction: epidemiology, mechanisms and management

JC Schefold, G Filippatos, G Hasenfuss… - Nature Reviews …, 2016 - nature.com
Heart failure (HF) is a major health-care problem and the prognosis of affected patients is
poor. HF often coexists with a number of comorbidities of which declining renal function is of …

[HTML][HTML] The natriuretic peptide system in heart failure: Diagnostic and therapeutic implications

K Kuwahara - Pharmacology & therapeutics, 2021 - Elsevier
Natriuretic peptides, which are activated in heart failure, play an important cardioprotective
role. The most notable of the cardioprotective natriuretic peptides are atrial natriuretic …

Organ dysfunction, injury and failure in acute heart failure: from pathophysiology to diagnosis and management. A review on behalf of the Acute Heart Failure …

VP Harjola, W Mullens, M Banaszewski… - European journal of …, 2017 - Wiley Online Library
Organ injury and impairment are commonly observed in patients with acute heart failure
(AHF), and congestion is an essential pathophysiological mechanism of impaired organ …

[HTML][HTML] Sympathetic nervous system activation and heart failure: Current state of evidence and the pathophysiology in the light of novel biomarkers

JA Borovac, D D'Amario, J Bozic… - World journal of …, 2020 - ncbi.nlm.nih.gov
Heart failure (HF) is a complex clinical syndrome characterized by the activation of at least
several neurohumoral pathways that have a common role in maintaining cardiac output and …

[HTML][HTML] Updates in anthracycline-mediated cardiotoxicity

CG Nebigil, L Désaubry - Frontiers in Pharmacology, 2018 - frontiersin.org
Cardiotoxicity is one of the main adverse effects of chemotheraphy, affecting the completion
of cancer therapies and the short-and long-term quality of life. Anthracyclines are currently …

[HTML][HTML] Left ventricular remodeling after myocardial infarction: from physiopathology to treatment

SA Leancă, D Crișu, AO Petriș, I Afrăsânie, A Genes… - Life, 2022 - mdpi.com
Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …

Targeting Cyclic Guanosine Monophosphate to Treat Heart Failure: JACC Review Topic of the Week

M Emdin, A Aimo, V Castiglione, G Vergaro… - Journal of the American …, 2020 - jacc.org
The significant morbidity and mortality associated with heart failure with reduced ejection
fraction (HFrEF) or heart failure with preserved ejection fraction (HFpEF) justify the search for …