The clinical impact of infections due to extended-spectrum β-lactamase (ESBL)-and/or
carbapenemase-producing Enterobacterales (Ent) has reached dramatic levels worldwide …

Appropriate antibiotic treatment for critically ill patients with serious Gram-negative infections
in the intensive care unit is crucial to minimize morbidity and mortality. Several new …

Studies showed different outcomes when comparing SAT to long antimicrobial therapy
(LAT). No generalization can be made on all sites of infections and different GNBs. Further …

The rapid diagnosis of bacterial strains is paramount for the management of healthcare
associated infections (HAIs) and combating the antimicrobial resistance (AMR), two of the …

This study aimed to examine specific niches and usage for the aztreonam/amoxicillin/
clavulanate combination and to use population pharmacokinetic simulations of clinical …

Sepsis, the most serious complication of infection, occurs when a cascade of potentially life-
threatening inflammatory responses is triggered. Potentially life-threatening septic shock is a …

Novel agents should be used in line with antimicrobial stewardship principles, aimed at
reducing selective pressure for antimicrobial resistance. However, this does not mean that …

The clinical aspects of persistent bacteremia (PB) caused by gram-negative rods (GNRs) in
terms of antimicrobial resistance (AMR) and PB clearance status are unclear. This …

In the past decade, the prevalence of multidrug-resistant gram-negative (MDR-GN) bacterial
infections has increased significantly, leading to higher rates of morbidity and mortality …

Simple Summary Emerging antimicrobial resistance is a major concern in both human and
veterinary medicine. Of particular concern is the emergence of extended-spectrum beta …