CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo

J Dietrich, R Han, Y Yang, M Mayer-Pröschel, M Noble - Journal of biology, 2006 - Springer
Background Chemotherapy in cancer patients can be associated with serious short-and
long-term adverse neurological effects, such as leukoencephalopathy and cognitive …

Disturbed microbial ecology in Alzheimer's disease: Evidence from the gut microbiota and fecal metabolome

J Xi, D Ding, H Zhu, R Wang, F Su, W Wu, Z Xiao… - BMC microbiology, 2021 - Springer
Background Gut microbiota (GMB) alteration has been reported to influence the Alzheimer's
disease (AD) pathogenesis through immune, endocrine, and metabolic pathways. This study …

Neutrophils in traumatic brain injury (TBI): friend or foe?

YW Liu, S Li, SS Dai - Journal of neuroinflammation, 2018 - Springer
Our knowledge of the pathophysiology about traumatic brain injury (TBI) is still limited.
Neutrophils, as the most abundant leukocytes in circulation and the first-line transmigrated …

Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency'hematopoiesis

AD Panopoulos, SS Watowich - Cytokine, 2008 - Elsevier
Neutrophils are phagocytes whose principal function is to maintain anti-bacterial immunity.
Neutrophils ingest and kill invading bacteria, releasing cytotoxic, chemotactic and …

Neuroprotection for ischaemic stroke: translation from the bench to the bedside

BA Sutherland, J Minnerup, JS Balami… - … Journal of Stroke, 2012 - journals.sagepub.com
Neuroprotection seeks to restrict injury to the brain parenchyma following an ischaemic
insult by preventing salvageable neurons from dying. The concept of neuroprotection has …

Mechanisms of neural plasticity following brain injury

T Wieloch, K Nikolich - Current opinion in neurobiology, 2006 - Elsevier
Brain insults cause rapid cell death, and a disruption of functional circuits, in the affected
regions. As the injured tissue recovers from events associated with cell death, regenerative …

A novel combinatorial therapy with pulp stem cells and granulocyte colony-stimulating factor for total pulp regeneration

K Iohara, M Murakami, N Takeuchi… - Stem cells …, 2013 - academic.oup.com
Abstract Treatment of deep caries with pulpitis is a major challenge in dentistry. Stem cell
therapy represents a potential strategy to regenerate the dentin-pulp complex, enabling …

A pilot cohort study of granulocyte colony-stimulating factor in the treatment of unresponsive thin endometrium resistant to standard therapies

N Gleicher, A Kim, T Michaeli, HJ Lee… - Human …, 2013 - academic.oup.com
STUDY QUESTION Is thin endometrium unresponsive to standard treatments expandable
by intrauterine perfusion with granulocyte colony-stimulating factor (G-CSF)? SUMMARY …

Physical activity and memory functions: are neurotrophins and cerebral gray matter volume the missing link?

A Flöel, R Ruscheweyh, K Krüger, C Willemer, B Winter… - Neuroimage, 2010 - Elsevier
Epidemiological studies reveal better cognitive function in physically active individuals.
Possible mediators for this effect are neurotrophins, which are up-regulated through physical …

In vitro microfluidic models for neurodegenerative disorders

T Osaki, Y Shin, V Sivathanu… - Advanced healthcare …, 2018 - Wiley Online Library
Microfluidic devices enable novel means of emulating neurodegenerative disease
pathophysiology in vitro. These organ‐on‐a‐chip systems can potentially reduce animal …