CADASIL from bench to bedside: disease models and novel therapeutic approaches

A Manini, L Pantoni - Molecular Neurobiology, 2021 - Springer
Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is a monogenic disease caused by NOTCH3 mutations …

Long-term caffeine treatment of Alzheimer mouse models ameliorates behavioural deficits and neuron loss and promotes cellular and molecular markers of …

M Stazi, S Lehmann, MS Sakib… - Cellular and Molecular …, 2021 - Springer
Epidemiological studies indicate that the consumption of caffeine, the most commonly
ingested psychoactive substance found in coffee, tea or soft drinks, reduces the risk of …

Increased generation of granule cells in adult Bcl‐2‐overexpressing mice: a role for cell death during continued hippocampal neurogenesis

HG Kuhn, M Biebl, D Wilhelm, M Li… - European journal of …, 2005 - Wiley Online Library
Programmed cell death is an important mechanism during brain development in order to
control neuronal cell numbers and to correctly form neuronal circuitries. Programmed cell …

Increased serum resistin but not G-CSF levels are associated in the pathophysiology of major depressive disorder: Findings from a case-control study

S Rahman, AA Shanta, S Daria, Z Nahar, M Shahriar… - PLoS …, 2022 - journals.plos.org
Background Many studies have predicted major depressive disorder (MDD) as the leading
cause of global health by 2030 due to its high prevalence, disability, and illness. However …

Neurorestoration after stroke

TD Azad, A Veeravagu, GK Steinberg - Neurosurgical focus, 2016 - thejns.org
Recent advancements in stem cell biology and neuromodulation have ushered in a battery
of new neurorestorative therapies for ischemic stroke. While the understanding of stroke …

Reviews: mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis

M LLorens-Martin, I Torres-Aleman… - The …, 2009 - journals.sagepub.com
This review addresses the role of serum insulin-like growth factor 1 (IGF1) as one
mechanism of adult neural plasticity, specifically, its regulation of hippocampal …

Changes in the secretome of tri-dimensional spheroid-cultured human mesenchymal stem cells in vitro by interleukin-1 priming

E Redondo-Castro, CJ Cunningham, J Miller… - Stem cell research & …, 2018 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are one of the most promising
candidates for the treatment of major neurological disorders. Desirable therapeutic …

Treatment with granulocyte colony-stimulating factor in patients with repetitive implantation failures and/or recurrent spontaneous abortions

W Würfel - Journal of reproductive immunology, 2015 - Elsevier
Granulocyte colony-stimulating factor (G-CSF) belongs to the family of colony-stimulating
factors (CSF). As the name suggests, it was initially identified as being able to target and …

Differential correlations between inflammatory cytokines and psychopathology in veterans with schizophrenia: potential role for IL-17 pathway

DH Dimitrov, S Lee, J Yantis, C Valdez… - Schizophrenia …, 2013 - Elsevier
Pro-inflammatory cytokines have been consistently reported to be elevated in schizophrenia
patients. However, it is not known whether cytokines influence the presentation of psychotic …

[HTML][HTML] Classic and novel stem cell niches in brain homeostasis and repair

R Lin, L Iacovitti - Brain research, 2015 - Elsevier
Neural stem cells (NSCs) critical for the continued production of new neurons and glia are
sequestered in distinct areas of the brain called stem cell niches. Until recently, only two …