Background: β-thalassaemia patients receive regular blood transfusion to thrive. Due to
antigen disparity between the blood donors and these patients they develop red cell …

Abstract Background and Objectives Recently, researchers have shown an increased
interest in thalassemia for detecting susceptible factors in alloimmunization development …

Our knowledge of the various clinical morbidities that thalassemia intermedia (TI) patients
endure has substantially increased over the past decade. It is mandatory to grasp a solid …

Hemostasis is a physiological well-controlled complex process in the body in which the
integrity of the circulatory system is maintained after vascular injury. This process consists of …

Background: The development of hemolytic alloantibodies and erythrocyte autoantibodies
complicates transfusion therapy in thalassemia patients. Methods: The frequency, causes …

Beta-thalassemia is one of the most frequently occurring hematological disorders in
[Removed for blinded peer-review]. Regular blood transfusion is required in almost all cases …

Objective We aimed to find out the frequency of alloimmunization in multitransfused β-
thalassemic patients, the most common alloantibodies involved, factors contributing to their …

Background: Patients with thalassemia major are clinically dependent on red blood cell
(RBC) transfusions. Performing multiple transfusions increase the risk of transfusion-related …

Red blood cell (RBC) alloantibodies, especially IgG class, are clinically significant because
of their association with hemolytic disease of newborns (HDN), hemolytic transfusion …

METHODS This single centre retrospective study was conducted at Afzaal Memorial
Thalassemia Foundation (AMTF), Karachi Pakistan. A total of 372 β Thalassemia major …