Extracellular miRNAs: from biomarkers to mediators of physiology and disease
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
S Zhou, J Jin, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
world. Although considerable progress has been made in the diagnosis, treatment and …
world. Although considerable progress has been made in the diagnosis, treatment and …
MicroRNA sequence codes for small extracellular vesicle release and cellular retention
Exosomes and other small extracellular vesicles (sEVs) provide a unique mode of cell-to-
cell communication in which microRNAs (miRNAs) produced and released from one cell are …
cell communication in which microRNAs (miRNAs) produced and released from one cell are …
miR-29b contributes to multiple types of muscle atrophy
A number of microRNAs (miRNAs, miRs) have been shown to play a role in skeletal muscle
atrophy, but their role is not completely understood. Here we show that miR-29b promotes …
atrophy, but their role is not completely understood. Here we show that miR-29b promotes …
[HTML][HTML] Oxidative stress, mitochondrial dysfunction, and respiratory chain enzyme defects in inflammatory myopathies
MG Danieli, E Antonelli, MA Piga, MF Cozzi… - Autoimmunity …, 2023 - Elsevier
We investigated the relationship between oxidative stress and inflammatory myopathies. We
searched in the current literature the role of mitochondria and respiratory chain defects as …
searched in the current literature the role of mitochondria and respiratory chain defects as …
Physical exercise and epigenetic modifications in skeletal muscle
Physical activity and sports play major roles in the overall health status of humans. It is well
known that regular exercise helps to lower the risk for a broad variety of health problems …
known that regular exercise helps to lower the risk for a broad variety of health problems …
Regulatory roles of microRNAs in diabetes
J Feng, W Xing, L Xie - International journal of molecular sciences, 2016 - mdpi.com
MicroRNAs (miRNAs), a class of endogenous small noncoding RNAs in eukaryotes, have
been recognized as significant regulators of gene expression through post-transcriptional …
been recognized as significant regulators of gene expression through post-transcriptional …
Myostatin: Basic biology to clinical application
P Esposito, D Picciotto, Y Battaglia, F Costigliolo… - Advances in clinical …, 2022 - Elsevier
Myostatin is a member of the transforming growth factor (TGF)-β superfamily. It is expressed
by animal and human skeletal muscle cells where it limits muscle growth and promotes …
by animal and human skeletal muscle cells where it limits muscle growth and promotes …
Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs: novel cardio-oncology insights from the joint 2019 meeting of the …
CG Tocchetti, P Ameri, RA de Boer… - Cardiovascular …, 2020 - academic.oup.com
In western countries, cardiovascular (CV) disease and cancer are the leading causes of
death in the ageing population. Recent epidemiological data suggest that cancer is more …
death in the ageing population. Recent epidemiological data suggest that cancer is more …
Epigenetic changes in healthy human skeletal muscle following exercise–a systematic review
Exercise training is continually challenging whole-body homeostasis, leading to
improvements in performance and health. Adaptations to exercise training are complex and …
improvements in performance and health. Adaptations to exercise training are complex and …