[HTML][HTML] Aryl hydrocarbon receptor (AhR) impairs circadian regulation: Impact on the aging process
A Salminen - Ageing Research Reviews, 2023 - Elsevier
Circadian clocks control the internal sleep-wake rhythmicity of 24 h which is synchronized by
the solar cycle. Circadian regulation of metabolism evolved about 2.5 billion years ago, ie …
the solar cycle. Circadian regulation of metabolism evolved about 2.5 billion years ago, ie …
Targeting aryl hydrocarbon receptor to prevent cancer in barrier organs
F Congues, P Wang, J Lee, D Lin, A Shahid… - Biochemical …, 2024 - Elsevier
The skin, lung, and gut are important barrier organs that control how the body reacts to
environmental stressors such as ultraviolet (UV) radiation, air pollutants, dietary …
environmental stressors such as ultraviolet (UV) radiation, air pollutants, dietary …
Regulatory Mechanism of the IL-33–IL-37 Axis via Aryl Hydrocarbon Receptor in Atopic Dermatitis and Psoriasis
G Tsuji, K Yamamura, K Kawamura… - International journal of …, 2023 - mdpi.com
Interleukin (IL)-33 and IL-37 have been identified as novel cytokines involved in various
inflammatory diseases. However, their specific roles remain largely unknown. Recent …
inflammatory diseases. However, their specific roles remain largely unknown. Recent …
Modulation of immunity by tryptophan microbial metabolites
S Li - Frontiers in Nutrition, 2023 - frontiersin.org
Tryptophan (Trp) is an essential amino acid that can be metabolized via endogenous and
exogenous pathways, including the Kynurenine Pathway, the 5-Hydroxyindole Pathway …
exogenous pathways, including the Kynurenine Pathway, the 5-Hydroxyindole Pathway …
DNA methylation clocks for estimating biological age in Chinese cohorts
Epigenetic clocks are accurate predictors of human chronological age based on the analysis
of DNA methylation (DNAm) at specific CpG sites. However, a systematic comparison …
of DNA methylation (DNAm) at specific CpG sites. However, a systematic comparison …
The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo [a] pyrene exposed F1 and F3 male medaka
ABSTRACT Benzo [a] pyrene (BaP) is ubiquitously present in the aquatic environment and
has been identified as a bone toxicant. Previous studies have demonstrated that ancestral …
has been identified as a bone toxicant. Previous studies have demonstrated that ancestral …
The kynurenine pathway in HIV, frailty and inflammaging
S Sultana, A Elengickal, H Bensreti… - Frontiers in …, 2023 - frontiersin.org
Kynurenine (Kyn) is a circulating tryptophan (Trp) catabolite generated by enzymes
including IDO1 that are induced by inflammatory cytokines such as interferon-gamma. Kyn …
including IDO1 that are induced by inflammatory cytokines such as interferon-gamma. Kyn …
AHR/TET2/NT5E axis downregulation is associated with the risk of systemic lupus erythematosus and its progression
HH Cheng, L Hung‐Ke, ML Sheu, CY Lee… - …, 2023 - Wiley Online Library
The prognosis of systemic lupus erythematosus (SLE) is unpredictable. This study aimed to
examine the regulatory mechanism of the AHR/TET2/NT5E pathway during SLE …
examine the regulatory mechanism of the AHR/TET2/NT5E pathway during SLE …
Aryl hydrocarbon receptor: Linking environment to aging process in elderly patients with asthma
T Yang, R Wan, W Tu, SN Avvaru, P Gao - Chinese medical journal, 2024 - mednexus.org
Aging is a significant risk factor for various diseases, including asthma, and it often leads to
poorer clinical outcomes, particularly in elderly individuals. It is recognized that age-related …
poorer clinical outcomes, particularly in elderly individuals. It is recognized that age-related …
Exposure to 3, 3′, 4, 4′, 5-Pentachlorobiphenyl (PCB126) Causes Widespread DNA Hypomethylation in Adult Zebrafish Testis
N Aluru, J Engelhardt - Toxicological Sciences, 2022 - academic.oup.com
Exposure to environmental toxicants during preconception has been shown to affect
offspring health and epigenetic mechanisms such as DNA methylation are hypothesized to …
offspring health and epigenetic mechanisms such as DNA methylation are hypothesized to …