Currently, metformin is the first-line medication to treat type 2 diabetes mellitus (T2DM) in
most guidelines and is used daily by> 200 million patients. Surprisingly, the mechanisms …

The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …

Excess body weight is a global health problem due to sedentary lifestyle and unhealthy diet,
affecting 2 billion population worldwide. Obesity is a major risk factor for metabolic diseases …

Nonresolving inflammation contributes to many diseases, including COVID-19 in its fatal and
long forms. Our understanding of inflammation is rapidly evolving. Like the immune system …

High iron is a risk factor for type 2 diabetes mellitus (T2DM) and affects most of its cardinal
features: decreased insulin secretion, insulin resistance, and increased hepatic …

Obesity is characterized by an increase in body weight associated with an exaggerated
enlargement of the adipose tissue. Obesity has serious negative effects because it is …

Background The development of the future food industry is heavily focused on plant-based
foods. These foods usually contain phytic acid (PA), which has been considered an anti …

The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

In this study, we designed and synthesized a novel class of 1, 3, 4-oxadiazolyl-containing β-
carboline derivatives, ie, compounds f1∼ f35 as potential α-glucosidase inhibitors. All the …

Abstract Background Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor,
has been extensively demonstrated to be associated with metabolic disorders, including …