Compression profiles of different molecular weight chitosans

F Alakayleh, I Rashid, MMH Al-Omari, K Al-Sou'od… - Powder Technology, 2016 - Elsevier
The compression behavior of hydrophilic chitosan has been investigated as a function of
molecular weight (MW), ranging from 8 to 100 kDa. Powder packing, plasticity, elasticity …

Comparison of the performance of two grades of metformin hydrochloride elaboration by means of the SeDeM system, compressibility, compactability, and process …

O Castaneda Hernandez… - Drug Development …, 2021 - Taylor & Francis
Quality by design, applied to the development of a pharmaceutical drug, demands scientific
methodologies, representing a source of information that will allow for a complete …

New insights into segregation during tabletting

S Lakio, S Siiriä, H Räikkönen, S Airaksinen… - International journal of …, 2010 - Elsevier
The aim of this study was to evaluate how different granule size distributions affect the tablet
compression process. The emphasis was on developing new analytic methods for …

Comparison of different chemometric and analytical methods for the prediction of particle size distribution in pharmaceutical powders

MC Sarraguça, AV Cruz, HR Amaral, PC Costa… - Analytical and …, 2011 - Springer
This work compares the estimation of the particle size distribution of a pharmaceutical
powder using near-infrared spectroscopy (NIRS), powder flowability properties, and …

Mechanical production of pellets for the application of entomopathogenic nematodes: factors that determine survival time of Steinernema glaseri

PT Matadamas-Ortiz, J Ruiz-Vega… - Biocontrol Science …, 2014 - Taylor & Francis
Applications of infective juveniles (IJ) of entomopathogenic nematodes (EPN) formulated in
pellets are still limited. This is principally due to limited advances in the technology of …

[图书][B] Process simulation and control for continuous pharmaceutical manufacturing of solid drug products

M Ierapetritou, MS Escotet-Espinoza, R Singh - 2017 - books.google.com
The current pharmaceutical process development and manufacturing paradigm is relatively
inefficient and poorly understood when compared to other industries. Whereas most …

Characterization of Acid Hydrolyzed Taro Boloso‐I (Colocasia esculenta Cultivar) Starch as a Diluent in Direct Compression of Tablets

S Gashaw, A Getachew, F Mola - Advances in Pharmacological …, 2024 - Wiley Online Library
Corn, wheat, rice, potato, and cassava starches have been widely used as pharmaceutical
excipients. However, the search for cost‐effective local starch alternatives is necessary due …

An investigation of the influence of process and formulation variables on mechanical properties of high shear granules using design of experiment

C Mangwandi, MJ Adams, MJ Hounslow… - International Journal of …, 2012 - Elsevier
Being able to predict the properties of granules from the knowledge of the process and
formulation variables is what most industries are striving for. This research uses …

A methodological approach for determining the effect of moisture content on the compaction properties of powders: granular hydroxyapatite

JB Wade, GP Martin, DF Long - Powder technology, 2013 - Elsevier
The effect of moisture on the compaction properties of hydroxyapatite (HA) was studied. A
single lot of commercially available HA was heated at various temperatures to provide …

Simulation modeling of a pharmaceutical tablet manufacturing process via wet granulation

Z Wang, Z Pan, D He, J Shi, S Sun, Y Hou - Complexity, 2019 - Wiley Online Library
The pharmaceutical tablet manufacturing process (PTMP) via wet granulation holds a critical
position in pharmaceutical industry. The interest in integrating mechanistic process …