Antimicrobial peptide 2K4L inhibits the inflammatory response in macrophages and Caenorhabditis elegans and protects against LPS-induced septic shock in mice

F Ji, G Tian, D Shang - Scientific Reports, 2024 - nature.com
Abstract 2K4L is a rationally designed analog of the short α-helical peptide temporin-1CEc,
a natural peptide isolated and purified from the skin secretions of the Chinese brown frog …

Intracellular bactericidal activity and action mechanism of MDP1 antimicrobial peptide against VRSA and MRSA in human endothelial cells

S Dashtbin, S Razavi, M Ganjali Koli, F Barneh… - Frontiers in …, 2024 - frontiersin.org
Introduction Staphylococcus aureus is a prominent cause of postoperative infections, often
persisting within host cells, leading to chronic infections. Conventional antibiotics struggle to …

Chensinin-1b Alleviates DSS-Induced Inflammatory Bowel Disease by Inducing Macrophage Switching from the M1 to the M2 Phenotype

Y Sun, H Li, X Duan, X Ma, C Liu, D Shang - Biomedicines, 2024 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder with an
increasing prevalence worldwide. Macrophage polarization is involved in the pathogenesis …

Cell-free supernatant-assisted biogenic silver nanoparticles enhance the antibacterial efficacy of communicating bacterial pathogens

R Srimathi, T Sondak, K Kim - Biotechnology and Bioprocess Engineering, 2024 - Springer
The use of nanoparticles (NPs) as an alternative to the current generation of conventional
antibiotics has exploded in the research community in recent years, as evidence of the …