The minefield of indeterminate thyroid nodules: could artificial intelligence be a suitable diagnostic tool?

V Fiorentino, C Pizzimenti, M Franchina… - Diagnostic …, 2023 - Elsevier
Artificial intelligence (AI) is assuming a central role in anatomic pathology for ancillary
diagnosis in histology and cytology. AI techniques can analyse large amounts of data and …

Prospective validation of ThyroSPEC molecular testing of indeterminate thyroid nodule cytology following diagnostic pathway optimization

P Stewardson, M Eszlinger, J Wu, M Khalil, A Box… - Thyroid, 2023 - liebertpub.com
Background: Molecular testing for cytologically indeterminate thyroid nodules (ITNs) is often
reported with incomplete data on clinical assessment and ultrasound malignancy risk …

Molecular Diagnostics and [18F]FDG-PET/CT in Indeterminate Thyroid Nodules: Complementing Techniques or Waste of Valuable Resources?

EJ de Koster, H Morreau, GS Bleumink… - Thyroid, 2024 - liebertpub.com
Background: An accurate preoperative workup of cytologically indeterminate thyroid nodules
(ITN) may rule out malignancy and avoid diagnostic surgery for benign nodules. This study …

[HTML][HTML] Appropriate and mindful measurement of serum calcitonin in patients with thyroid nodules. A white paper

P Trimboli, P Valderrabano, F Pitoia, A Piccardo… - Endocrine, 2024 - Springer
Medullary thyroid carcinoma (MTC) is an infrequent thyroid malignancy that is often
diagnosed at advanced stage with consequent poor prognosis. Thus, the earlier the …

[HTML][HTML] Could a novel category of molecular testing be emerging?

C Ferraz, LS Ward - Chinese Clinical Oncology, 2023 - cco.amegroups.org
Thyroid nodules have been increasingly common in our daily lives and the combination of
thyroid ultrasonography and fine needle aspiration biopsy (FNAB) remains the gold …

Clinical characteristics and treatment patterns of patients with NTRK fusion–positive solid tumors: A multisite cohort study at US academic cancer centers

C Willis, T Au, A Hejazi, C Griswold… - Journal of managed …, 2024 - jmcp.org
BACKGROUND: Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are rare
oncogenic drivers prevalent in 0.3% of solid tumors. They are most common in salivary …

[HTML][HTML] The value of ACR, European, Korean, and ATA ultrasound risk stratification systems combined with RAS mutations for detecting thyroid carcinoma in …

L Scappaticcio, N Di Martino, P Caruso, P Ferrazzano… - Hormones, 2024 - Springer
Purpose The aim of this study was to evaluate the diagnostic value of four commonly utilized
ultrasound (US) RSSs, namely, the American College of Radiology [ACR], European [EU] …

Integrated gene profiling of fine‐needle aspiration sample improves lymph node metastasis risk stratification for thyroid cancer

W Zhang, X Yun, T Xu, X Wang, Q Li, T Zhang… - Cancer …, 2023 - Wiley Online Library
Background Lymph node metastasis risk stratification is crucial for the surgical decision‐
making of thyroid cancer. This study investigated whether the integrated gene profiling …

Clinical characteristics and treatment patterns of patients with NTRK fusion–positive solid tumors: A multisite cohort study at US academic cancer centers

MB Schabath, J Thompson, J Malhotra… - RACIAL AND SOCIAL …, 2024 - jmcp.org
ABSTRACT BACKGROUND: Neurotrophic tyrosine receptor kinase (NTRK) gene fusions
are rare oncogenic drivers prevalent in 0.3% of solid tumors. They are most common in …

[HTML][HTML] Illuminating thyroid cancer

N Davies - thepharmaletter.com
Thyroid cancer is a rare cancer that encompasses several variations (Table 1). 1-3 The
incidence is higher in women compared to men. 4 Worldwide, the most common age at …