[HTML][HTML] Advances in our understanding of oxylipins derived from dietary PUFAs
M Gabbs, S Leng, JG Devassy, M Monirujjaman… - Advances in …, 2015 - Elsevier
Oxylipins formed from polyunsaturated fatty acids (PUFAs) are the main mediators of PUFA
effects in the body. They are formed via cyclooxygenase, lipoxygenase, and cytochrome …
effects in the body. They are formed via cyclooxygenase, lipoxygenase, and cytochrome …
Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events
D Mozaffarian, JHY Wu - Journal of the American College of Cardiology, 2011 - jacc.org
We reviewed available evidence for cardiovascular effects of n-3 polyunsaturated fatty acid
(PUFA) consumption, focusing on long chain (seafood) n-3 PUFA, including their principal …
(PUFA) consumption, focusing on long chain (seafood) n-3 PUFA, including their principal …
Therapeutic potential of omega-3 fatty acid-derived epoxyeicosanoids in cardiovascular and inflammatory diseases
WH Schunck, A Konkel, R Fischer… - Pharmacology & …, 2018 - Elsevier
Numerous benefits have been attributed to dietary long-chain omega-3 polyunsaturated fatty
acids (n-3 LC-PUFAs), including protection against cardiac arrhythmia, triglyceride-lowering …
acids (n-3 LC-PUFAs), including protection against cardiac arrhythmia, triglyceride-lowering …
P-450 Metabolites of Arachidonic Acid in the Control of Cardiovascular Function
RJ Roman - Physiological reviews, 2002 - journals.physiology.org
Recent studies have indicated that arachidonic acid is primarily metabolized by cytochrome
P-450 (CYP) enzymes in the brain, lung, kidney, and peripheral vasculature to 20 …
P-450 (CYP) enzymes in the brain, lung, kidney, and peripheral vasculature to 20 …
[HTML][HTML] (n-3) fatty acids and cardiovascular health: are effects of EPA and DHA shared or complementary?
D Mozaffarian, JHY Wu - The Journal of nutrition, 2012 - Elsevier
Considerable research supports cardiovascular benefits of consuming omega-3 PUFA, also
known as (n-3) PUFA, from fish or fish oil. Whether individual long-chain (n-3) PUFA have …
known as (n-3) PUFA, from fish or fish oil. Whether individual long-chain (n-3) PUFA have …
Cytochrome P450 epoxygenase pathway of polyunsaturated fatty acid metabolism
AA Spector, HY Kim - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2015 - Elsevier
Polyunsaturated fatty acids (PUFA) are oxidized by cytochrome P450 epoxygenases to
PUFA epoxides which function as potent lipid mediators. The major metabolic pathways of …
PUFA epoxides which function as potent lipid mediators. The major metabolic pathways of …
Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function
AA Spector, X Fang, GD Snyder, NL Weintraub - Progress in lipid research, 2004 - Elsevier
Epoxyeicosatrienoic acids (EETs), which are synthesized from arachidonic acid by
cytochrome P450 epoxygenases, function primarily as autocrine and paracrine effectors in …
cytochrome P450 epoxygenases, function primarily as autocrine and paracrine effectors in …
Fish oil—how does it reduce plasma triglycerides?
GC Shearer, OV Savinova, WS Harris - … BBA)-Molecular and Cell Biology of …, 2012 - Elsevier
Long chain omega-3 fatty acids (FAs) are effective for reducing plasma triglyceride (TG)
levels. At the pharmaceutical dose, 3.4 g/day, they reduce plasma TG by about 25–50% after …
levels. At the pharmaceutical dose, 3.4 g/day, they reduce plasma TG by about 25–50% after …
[HTML][HTML] Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of ω-3 fatty acids
C Arnold, M Markovic, K Blossey, G Wallukat… - Journal of Biological …, 2010 - ASBMB
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) protect against
cardiovascular disease by largely unknown mechanisms. We tested the hypothesis that EPA …
cardiovascular disease by largely unknown mechanisms. We tested the hypothesis that EPA …
Old and new generation lipid mediators in acute inflammation and resolution
MJ Stables, DW Gilroy - Progress in lipid research, 2011 - Elsevier
Originally regarded as just membrane constituents and energy storing molecules, lipids are
now recognised as potent signalling molecules that regulate a multitude of cellular …
now recognised as potent signalling molecules that regulate a multitude of cellular …