The Nucleotide-binding domain leucine-rich repeat and pyrin domain containing receptor 3
(NLRP3), a member of the nucleotide-binding oligomerization domain (NOD) like receptors …

The immune response plays a pivotal role in the pathogenesis of diseases. Toll-like receptor
4 (TLR4), as an intrinsic immune receptor, exhibits widespread in vivo expression and its …

The increasing incidence of colitis and the side effects of its therapeutic drugs have led to
the search for compounds of natural origin, including phenolics, as new treatments for colitis …

Endometriosis is closely associated with ectopic focal inflammation and immunosuppressive
microenvironment. Multiple types of pattern recognition receptors (PRRs) are present in the …

Background Neutrophilic airway inflammation is a challenge in asthma management and is
associated with poor patient prognosis. Mucin 1 (MUC1), which contains a cytoplasmic tail …

The immunomodulatory effect of divalent manganese cations (Mn2+), such as activation of
the cGAS− STING pathway or NLRP3 inflammasomes, positions them as adjuvants for …

Irisin is an exercise-induced myokine that alleviates inflammation and obesity. The induction
of anti-inflammatory (M2) macrophage is facilitated for treatment of sepsis and associated …

Chikungunya virus (CHIKV) is an emerging viral infectious agent with the potential of
causing pandemic. There is neither a protective vaccine nor an approved drug against the …

Gliomas are the most common brain tumors characterized by complicated heterogeneity.
The genetic, molecular, and histological pathology of gliomas is characterized by high neuro …

African swine fever (ASF), caused by ASF virus (ASFV) infection, poses a huge threat to the
pork industry owing to ineffective preventive and control measures. Hence, there is an …