Modulation of FABP4 hypomethylation by DNMT1 and its inverse interaction with miR-148a/152 in the placenta of preeclamptic rats and HTR-8 cells

A Yang, H Zhang, Y Sun, Y Wang, X Yang, X Yang… - Placenta, 2016 - Elsevier
Inflammation and dysregulated lipid metabolism are involved in the pathogenesis of
preeclampsia, and fatty acid binding protein 4 (FABP4) is known to regulate both …

Deer antler extract potentially facilitates xiphoid cartilage growth and regeneration and prevents inflammatory susceptibility by regulating multiple functional genes

M Guan, D Pan, M Zhang, X Leng, B Yao - Journal of Orthopaedic Surgery …, 2021 - Springer
Background Deer antler is a zoological exception due to its fantastic characteristics,
including amazing growth rate and repeatable regeneration. Deer antler has been used as a …

The obesogen bisphenol A promotes adipogenesis in canine adipose-derived stem cells: Potential implication in dog obesity

EJ Park, S Lee, JY Kim, J Choi, YS Lee, M Park… - Chemosphere, 2024 - Elsevier
The growing number of companion dogs has contributed to a rapidly growing market for pet
products, including dog toys. However, little is known about the hazardous substances …

The lipid side of bone marrow adipocytes: how tumor cells adapt and survive in bone

JD Diedrich, MK Herroon, E Rajagurubandara… - Current osteoporosis …, 2018 - Springer
Abstract Purpose of Review Bone marrow adipocytes have emerged in recent years as key
contributors to metastatic progression in bone. In this review, we focus specifically on their …

Fatty acid binding protein 4 has prognostic value in peripheral artery disease

B Li, A Zamzam, MH Syed, N Djahanpour, S Jain… - Journal of Vascular …, 2023 - Elsevier
Objective Peripheral artery disease (PAD) remains undertreated, despite its association with
major amputation and mortality. This is partly due to a lack of available disease biomarkers …

Hydrogen sulfide modulates high glucose-induced NLRP3 inflammasome activation in 3T3-L1 adipocytes

TX Hu, NN Zhang, Y Ruan… - Experimental and …, 2020 - spandidos-publications.com
Activation of the NACHT leucine rich repeat and pyd domains-containing 3 (NLRP3)
inflammasome plays an important role in the initiation of inflammation in adipose tissue in …

Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors

H Kühne, U Obst-Sander, B Kuhn, A Conte… - Bioorganic & medicinal …, 2016 - Elsevier
Dual inhibition of fatty acid binding proteins 4 and 5 (FABP4 and FABP5) is expected to
provide beneficial effects on a number of metabolic parameters such as insulin sensitivity …

Prostaglandin E2 impairs osteogenic and facilitates adipogenic differentiation of human bone marrow stromal cells

C Noack, U Hempel, C Preissler, P Dieter - … , Leukotrienes and Essential …, 2015 - Elsevier
The synthetic glucocorticoid dexamethasone (dex) is a mandatory additive to induce
osteogenic differentiation of bone marrow stromal cell (BMSC) in vitro; however it is also …

Energy metabolic disorder is a major risk factor in severe influenza virus infection: Proposals for new therapeutic options based on animal model experiments

H Kido, IL Indalao, H Kim, T Kimoto, S Sakai… - Respiratory …, 2016 - Elsevier
Severe influenza is characterized by cytokine storm and multiorgan failure. Influenza
patients with underlying diseases show a rapid progression in disease severity. The major …

Potential roles of brain barrier dysfunctions in the early stage of Alzheimer's disease

W Jian, Z Zhang, S Chu, Y Peng, N Chen - Brain Research Bulletin, 2018 - Elsevier
Though Alzheimer's disease (AD) has been studied for more than a century, to date, no drug
has provided a definitive cure. The slow development of the disease and the time lag …