The prostaglandin derivatives are thought to lower intraocular pressure (IOP) primarily by
increasing uveoscleral outflow. The ocular side effect, hyperemia, appears to occur via a …

Since its introduction in 1996, use of brimonidine tartrate 0.2% ophthalmic solution
(Alphagan®, Allergan), a highly selective 2-adrenergic agonist, has become increasingly …

A fixed combination of bimatoprost/timolol eye drop solution is used to manage the elevated
intra-ocular pressure in glaucoma patients, including individuals whose condition is poorly …

OBJECTIVE: To compare the safety, tolerability, and efficacy of bimatoprost 0.03% instilled
once daily or twice daily with timolol 0.5% twice daily. DESIGN: Multicenter, 3-month …

Epithelial-neuronal signaling is essential for sensory encoding in touch, itch, and
nociception; however, little is known about the release mechanisms and neurotransmitter …

Background The success of oral propranolol for treatment of infantile hemangiomas (IHs)
has led practitioners to use topical β‐blockers. In preterm infants, clinicians frequently turn to …

PURPOSE: To determine the impact of coadminstration of systemic β-blockers on the ocular
hypotensive efficacy and safety of topical timolol, a nonselective β-blocker, and that of …

Glaucoma is the leading cause of irreversible blindness worldwide. As a chronic disease,
glaucoma presents a significant burden to the individual, health‐care provider and the …

PURPOSE: To compare the 24-hour diurnal ocular hypotensive efficacy of two dosing
regimens of latanoprost, once daily (8 am or 10 pm), vs timolol maleate, twice daily …

In this work, a rapid and efficient procedure named ultrasound meliorated dispersive micro
solid-phase extraction followed by high performance liquid chromatography-ultra violet …