Chronic stress and oxidative stress as common factors of the pathogenesis of depression and Alzheimer's disease: The role of antioxidants in prevention and …

G Juszczyk, J Mikulska, K Kasperek, D Pietrzak… - Antioxidants, 2021 - mdpi.com
There is a growing body of scientific research showing the link between depression and
dementia in Alzheimer's disease (AD). The chronic stress contributes to the formation of …

Phenolic Compounds of Rhodiola rosea L. as the Potential Alternative Therapy in the Treatment of Chronic Diseases

J Bernatoniene, V Jakstas… - International journal of …, 2023 - mdpi.com
The roots and rhizomes of Rhodiola rosea L.(Crassulaceae), which is widely growing in
Northern Europe, North America, and Siberia, have been used since ancient times to …

[HTML][HTML] Salidroside attenuates acute lung injury via inhibition of inflammatory cytokine production

D Song, M Zhao, L Feng, P Wang, Y Li, W Li - Biomedicine & …, 2021 - Elsevier
Acute lung injury is a fatal condition characterized by excessive inflammation responses.
Salidroside, the active constituent of Rhodiola rosea, possesses properties including anti …

[HTML][HTML] Salidroside alleviates oxidative stress in dry eye disease by activating autophagy through AMPK-Sirt1 pathway

Q Liang, R Guo, JR Tsao, Y He, C Wang, J Jiang… - International …, 2023 - Elsevier
Dry eye disease (DED) is a multifactorial disease, and oxidative stress plays a crucial role in
its pathogenesis. Recently, multiple studies have shown that upregulation of autophagy can …

Salidroside alleviates hepatic ischemia–reperfusion injury during liver transplant in rat through regulating TLR-4/NF-κB/NLRP3 inflammatory pathway

Y Liu, Z Lei, H Chai, Q Kang, X Qin - Scientific reports, 2022 - nature.com
Salidroside has anti-inflammatory, antioxidant and hepatoprotective properties. However, its
effect on hepatic ischemia–reperfusion injury (IRI), an unavoidable side effect associated …

[HTML][HTML] Effect of Rhodiola rosea Rhizome and Punica granatum Fruit Peel on the Metabolic Processes and Physiological Activity of Rats Fed with Excessively Fat Diet

M Lieshchova, V Brygadyrenko - Food Technology and Biotechnology, 2023 - hrcak.srce.hr
Sažetak Research background. Rhodiola rosea (golden root) and Punica granatum
(pomegranate), as well as a number of other species of medicinal plants, exert an array of …

Phenols and terpenoids: Natural products as inhibitors of NLRP3 inflammasome in cardiovascular diseases

F Hua, L Shi, P Zhou - Inflammopharmacology, 2022 - Springer
Inflammatory infiltration has been implicated in the pathogenesis of cardiovascular diseases
(CVDs). The NLRP3 inflammasome is involved in the development of several types of CVDs …

Salidroside attenuates myocardial remodeling in DOCA-salt-induced mice by inhibiting the endothelin 1 and PI3K/AKT/NFκB signaling pathways

Q Liu, Q Luo, B Zhong, K Tang, X Chen, S Yang… - European Journal of …, 2024 - Elsevier
Myocardial remodeling, which occurs in the final stage of cardiovascular diseases such as
hypertension, can ultimately result in heart failure. However, the pathogenesis of myocardial …

Rhodiola rosea L. Extract, a Known Adaptogen, Evaluated in Experimental Arthritis

F Drafi, K Bauerova, M Chrastina, M Taghdisiesfejír… - Molecules, 2023 - mdpi.com
Rhodiola rosea L. extract (RSE) is mostly known for its adaptogen properties, but not for its
antiarthritic activities, therefore monotherapy and combination with low-dose methotrexate …

Angiopep-2 modified dual drug-loaded liposomes with brain targeting functionality mitigate Alzheimer's disease-related symptoms in APP/PS-1 mice

X Zhang, N Shi, M Chen, M Liu, R Ju, Y Liu… - Journal of Drug …, 2023 - Taylor & Francis
The blood–brain barrier (BBB) is a barrier that maintains brain homeostasis, but it is also
one of the major problems that must be overcome in the development of Alzheimer's disease …