The role of macrophages in the development of acute and chronic inflammatory lung diseases
JW Lee, W Chun, HJ Lee, JH Min, SM Kim, JY Seo… - Cells, 2021 - mdpi.com
Macrophages play an important role in the innate and adaptive immune responses of organ
systems, including the lungs, to particles and pathogens. Cumulative results show that …
systems, including the lungs, to particles and pathogens. Cumulative results show that …
Airway mucus and asthma: the role of MUC5AC and MUC5B
Asthma is characterized by mucus abnormalities. Airway epithelial hyperplasia and
metaplasia result in changes in stored and secreted mucin and the production of a …
metaplasia result in changes in stored and secreted mucin and the production of a …
Airway mucus, inflammation and remodeling: emerging links in the pathogenesis of chronic lung diseases
Z Zhou-Suckow, J Duerr, M Hagner, R Agrawal… - Cell and tissue …, 2017 - Springer
Airway mucus obstruction is a hallmark of many chronic lung diseases including rare genetic
disorders such as cystic fibrosis (CF) and primary ciliary dyskinesia, as well as common lung …
disorders such as cystic fibrosis (CF) and primary ciliary dyskinesia, as well as common lung …
Development of a functional airway-on-a-chip by 3D cell printing
We used 3D cell printing to emulate an airway coupled with a naturally-derived blood vessel
network in vitro. Decellularized extracellular matrix bioink derived from porcine tracheal …
network in vitro. Decellularized extracellular matrix bioink derived from porcine tracheal …
The mucus barrier to inhaled gene therapy
Recent evidence suggests that the airway mucus gel layer may be impermeable to the viral
and synthetic gene vectors used in past inhaled gene therapy clinical trials for diseases like …
and synthetic gene vectors used in past inhaled gene therapy clinical trials for diseases like …
Tear film mucins: front line defenders of the ocular surface; comparison with airway and gastrointestinal tract mucins
The ocular surface including the cornea and conjunctiva and its overlying tear film are the
first tissues of the eye to interact with the external environment. The tear film is complex …
first tissues of the eye to interact with the external environment. The tear film is complex …
Mechanisms of airway epithelial injury and abnormal repair in asthma and COPD
KL Raby, C Michaeloudes, J Tonkin, KF Chung… - Frontiers in …, 2023 - frontiersin.org
The airway epithelium comprises of different cell types and acts as a physical barrier
preventing pathogens, including inhaled particles and microbes, from entering the lungs …
preventing pathogens, including inhaled particles and microbes, from entering the lungs …
Gel-forming mucins form distinct morphologic structures in airways
LS Ostedgaard, TO Moninger… - Proceedings of the …, 2017 - National Acad Sciences
Gel-forming mucins, the primary macromolecular components of airway mucus, facilitate
airway clearance by mucociliary transport. In cystic fibrosis (CF) altered mucus properties …
airway clearance by mucociliary transport. In cystic fibrosis (CF) altered mucus properties …
Cellular and molecular biology of airway mucins
EP Lillehoj, K Kato, W Lu, KC Kim - … review of cell and molecular biology, 2013 - Elsevier
Airway mucus constitutes a thin layer of airway surface liquid with component
macromolecules that covers the luminal surface of the respiratory tract. The major function of …
macromolecules that covers the luminal surface of the respiratory tract. The major function of …
[HTML][HTML] Anti-inflammatory effect of quercetin-loaded microemulsion in the airways allergic inflammatory model in mice
AP Rogerio, CL Dora, EL Andrade, JS Chaves… - Pharmacological …, 2010 - Elsevier
Quercetin is a plant-derived flavonoid widely known by its anti-oxidant and anti-inflammatory
properties, but its oral bioavailability is very poor and this becomes difficult to assess its …
properties, but its oral bioavailability is very poor and this becomes difficult to assess its …