Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment

S Qi, N Duan, IM Khan, X Dong, Y Zhang, S Wu… - Biotechnology …, 2022 - Elsevier
Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …

Potential alternatives of animal proteins for sustainability in the food sector

P Kumar, N Mehta, AA Abubakar… - Food Reviews …, 2023 - Taylor & Francis
With the ever-increasing global population, it is impossible to meet the demand for animal
protein by relying only on conventional methods due to the depleting natural resources. It is …

A comprehensive review of oyster peptides: Preparation, characterisation and bioactivities

L Hao, X Wang, Y Cao, J Xu, C Xue - Reviews in Aquaculture, 2022 - Wiley Online Library
Oysters are a healthy and excellent source of lean protein (content up to 45%–57%). In
addition, polypeptides extracted from hydrolysis of oyster protein by enzymatic hydrolysis or …

[HTML][HTML] Technological interventions in improving the functionality of proteins during processing of meat analogs

P Kumar, N Sharma, MA Ahmed, AK Verma… - Frontiers in …, 2022 - frontiersin.org
Meat analogs have opened a new horizon of opportunities for developing a sustainable
alternative for meat and meat products. Proteins are an integral part of meat analogs and …

[HTML][HTML] Peptidomimetics in cancer targeting

MM Gomari, S Abkhiz, TG Pour, E Lotfi, N Rostami… - Molecular …, 2022 - Springer
The low efficiency of treatment strategies is one of the main obstacles to developing cancer
inhibitors. Up to now, various classes of therapeutics have been developed to inhibit cancer …

Structural evolution of Delta lineage of SARS-CoV-2

MM Gomari, P Tarighi, E Choupani, S Abkhiz… - International journal of …, 2023 - Elsevier
One of the main obstacles in prevention and treatment of COVID-19 is the rapid evolution of
the SARS-CoV-2 Spike protein. Given that Spike is the main target of common treatments of …

Biomimetic one-pot preparation of surface biofunctionalized silica-coated magnetic composites for dual enzyme oriented immobilization without pre-purification

H Ge, X Liu, H Yuan, G Zhang - Enzyme and Microbial Technology, 2023 - Elsevier
Highlights•Surface modified silica-coated magnetic composites are biomimetically prepared
in one-pot.•The mild and efficient process guarantees the function of SpyCatcher with …

Fabrication of Fe3O4@ SiO2@ PDA-Ni2+ nanoparticles for one-step affinity immobilization and purification of His-tagged glucose dehydrogenase

JY Huang, S Yu, RF Li, KK Han, YW Zhang - Process Biochemistry, 2023 - Elsevier
To avoid the additional purification procedures required before immobilization, the Fe 3 O
4@ SiO 2@ polydopamine (PDA)-Ni 2+ magnetic nanoparticles (MNPs) were prepared to …

Recombinant protein purification and immobilization strategies based on peptides with dual affinity to iron oxide and silica

TQ Aguiar, L Domingues - Biotechnology Journal, 2023 - Wiley Online Library
Iron oxide and silica‐based materials have emerged as attractive protein purification and
immobilization matrices. His6 has been reported as an effective affinity tag for both iron …

Toxicity of trastuzumab for breast cancer spheroids: application of a novel on-a-chip concentration gradient generator

S Shahrivari, N Aminoroaya, R Ghods, H Latifi… - Biochemical …, 2022 - Elsevier
Evaluating the effectiveness of drugs on an individual basis before prescribing them has an
influential role in choosing a successful treatment plan. The advent of microfluidic devices …