Lymphoproliferative disorders in patients with rheumatoid arthritis in the era of widespread use of methotrexate: a review of the literature and current perspective
M Harigai - Modern rheumatology, 2018 - academic.oup.com
Lymphoproliferative disorders (LPD) in patients receiving methotrexate (MTX) have gained
strong attention. In this article, I reviewed the basic and clinical findings of this issue. Patients …
strong attention. In this article, I reviewed the basic and clinical findings of this issue. Patients …
[HTML][HTML] Analysis of antibody binding specificities in twin and SNP-genotyped cohorts reveals that antiviral antibody epitope selection is a heritable trait
Human immune responses to viral infections are highly variable, but the genetic factors that
contribute to this variability are not well characterized. We used VirScan, a high-throughput …
contribute to this variability are not well characterized. We used VirScan, a high-throughput …
Germline mutations in Protection of Telomeres 1 in two families with Hodgkin lymphoma
ML McMaster, C Sun, MT Landi… - British journal of …, 2018 - Wiley Online Library
In a previous whole exome sequencing of patients from 41 families with Hodgkin lymphoma,
we identified two families with distinct heterozygous rare coding variants in POT 1 (D224N …
we identified two families with distinct heterozygous rare coding variants in POT 1 (D224N …
MINI-review of Epstein-Barr virus involvement in multiple sclerosis etiology and pathogenesis
F Aloisi, AH Cross - Journal of Neuroimmunology, 2022 - Elsevier
Epstein-Barr virus (EBV) is the infectious agent that shows the strongest association with
multiple sclerosis (MS). EBV is a ubiquitous double stranded DNA herpes virus that …
multiple sclerosis (MS). EBV is a ubiquitous double stranded DNA herpes virus that …
HLA class I and II diversity contributes to the etiologic heterogeneity of non-Hodgkin lymphoma subtypes
SS Wang, M Carrington, SI Berndt, SL Slager… - Cancer research, 2018 - AACR
A growing number of loci within the human leukocyte antigen (HLA) region have been
implicated in non-Hodgkin lymphoma (NHL) etiology. Here, we test a complementary …
implicated in non-Hodgkin lymphoma (NHL) etiology. Here, we test a complementary …
Promising drugs and treatment options for pediatric and adolescent patients with Hodgkin lymphoma
V De Re, O Repetto, L Mussolin, G Brisotto… - Frontiers in Cell and …, 2022 - frontiersin.org
Currently-available therapies for newly-diagnosed pediatric and adolescent patients with
Hodgkin lymphoma result in> 95% survival at 5 years. Long-term survivors may suffer from …
Hodgkin lymphoma result in> 95% survival at 5 years. Long-term survivors may suffer from …
Immune response in LPD during methotrexate administration (MTX-LPD) in rheumatoid arthritis patients
S Saito, T Takeuchi - Journal of clinical and experimental …, 2019 - jstage.jst.go.jp
Methotrexate (MTX) is known as a first-line synthetic disease-modifying anti-rheumatic drug
(DMARD) for the treatment of rheumatoid arthritis (RA). Although the risk of LPD …
(DMARD) for the treatment of rheumatoid arthritis (RA). Although the risk of LPD …
CD4+ Cytotoxic T cells involved in the development of EBV-associated diseases
M Ruiz-Pablos - Pathogens, 2022 - mdpi.com
Activated cytotoxic CD4 T cells (HLA-DR+) play an important role in the control of EBV
infection, especially in cells with latency I (EBNA-1). One of the evasion mechanisms of …
infection, especially in cells with latency I (EBNA-1). One of the evasion mechanisms of …
The role of HLA variation in lymphoma aetiology and survival
Epidemiologic and laboratory evidence has consistently supported a strong inflammatory
and immune component for lymphoma aetiology. These studies have consistently implicated …
and immune component for lymphoma aetiology. These studies have consistently implicated …