Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …

The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …

Endocannabinoids are among the most powerful modulators of synaptic transmission
throughout the nervous system, and yet little is understood about the release of …

Endocannabinoids (eCBs) exert major control over neuronal activity by activating
cannabinoid receptors (CBRs). The functionality of the eCB system is primarily ascribed to …

Cannabidiol (CBD) is a major non-intoxicating component of cannabis and possesses anti-
epileptic, anxiolytic and anti-hyperalgesic properties. The mechanism of action of CBD in …

Objective: This review consists of three parts, representing three different possibilities of
interactions between cannabinoid receptor ligands of both exogenous and endogenous …

Most neurodegenerative disorders (NDD s) are characterized by cognitive impairment and
other neurological defects. The definite cause of and pathways underlying the progression …

Anandamide (N-arachidonoylethanolamine) is known to be an endogenous ligand of
cannabinoid and vanilloid receptors. Its congeners (collectively referred to as N …

This review focuses on the role of the peripheral nervous system in cutaneous biology and
disease. During the last few years, a modern concept of an interactive network between …

In the nineteenth century, marijuana was prescribed by physicians for maladies ranging from
eating disorders to rabies. However, as newer, more effective drugs were discovered and as …