Functional relevance of endocannabinoid-dependent synaptic plasticity in the central nervous system

SM Augustin, DM Lovinger - ACS chemical neuroscience, 2018 - ACS Publications
The endocannabinoid (eCB) signaling system plays a key role in short-term and long-term
synaptic plasticity in brain regions involved in various neural functions ranging from action …

Cannabinoid receptors and the regulation of bone mass

I Bab, A Zimmer - British journal of pharmacology, 2008 - Wiley Online Library
A functional endocannabinoid system is present in several mammalian organs and tissues.
Recently, endocannabinoids and their receptors have been reported in the skeleton …

The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis

M Maccarrone, A Finazzi-Agro - Cell Death & Differentiation, 2003 - nature.com
Endocannabinoids are a new class of lipid mediators, which include amides, esters and
ethers of long-chain polyunsaturated fatty acids. Anandamide (N-arachidonoylethanolamine …

A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior

RJ McLaughlin, MN Hill, BB Gorzalka - Neuroscience & Biobehavioral …, 2014 - Elsevier
The prefrontal cortex (PFC) provides executive control of the brain in humans and rodents,
coordinating cognitive, emotional, and behavioral responses to threatening stimuli and …

Endocannabinoids in synaptic plasticity and neuroprotection

JY Xu, C Chen - The Neuroscientist, 2015 - journals.sagepub.com
Endocannabinoids (eCBs) are endogenous lipid mediators involved in a variety of
physiological, pharmacological, and pathological processes. While activation of the eCB …

N-acylethanolamines, anandamide and food intake

HS Hansen, TA Diep - Biochemical pharmacology, 2009 - Elsevier
Anandamide and the other N-acylethanolamines, eg oleoylethanolamide (OEA),
palmitoylethanolamide (PEA), and linoleoylethanolamide (LEA), may be formed by several …

The endocannabinoid system in human keratinocytes: evidence that anandamide inhibits epidermal differentiation through CB1 receptor-dependent inhibition of …

M Maccarrone, M Di Rienzo, N Battista… - Journal of Biological …, 2003 - ASBMB
Anandamide (AEA), a prominent member of the endogenous ligands of cannabinoid
receptors (endocannabinoids), is known to affect several functions of brain and peripheral …

Is there a role for the endocannabinoid system in the etiology and treatment of melancholic depression?

MN Hill, BB Gorzalka - Behavioural pharmacology, 2005 - journals.lww.com
With advances in basic and clinical neuroscience, many gaps have appeared in the
traditional monoamine theory of depression that have led to reformulation of the hypotheses …

The N‐Acylethanolamine‐Hydrolyzing Acid Amidase (NAAA)

K Tsuboi, N Takezaki, N Ueda - Chemistry & biodiversity, 2007 - Wiley Online Library
Bioactive N‐acylethanolamines, including the endocannabinoid anandamide and anti‐
inflammatory N‐palmitoylethanolamine, are hydrolyzed to fatty acids and ethanolamine in …

Pharmacological and therapeutic secrets of plant and brain (endo) cannabinoids

LO Hanuš - Medicinal research reviews, 2009 - Wiley Online Library
Research on the chemistry and pharmacology of cannabinoids and endocannabinoids has
reached enormous proportions, with approximately 15,000 articles on Cannabis sativa L …