Background In acute asthma inhaled beta₂‐agonists are often administered by nebuliser to
relieve bronchospasm, but some have argued that metered‐dose inhalers with a holding …

OBJECTIVE: To develop a set of comprehensive, standardized evidence-based guidelines
for the assessment and treatment of acute asthma in adults in the emergency setting …

Objective: To compare the effect of bronchodilator delivery by use of a metered-dose inhaler
(MDI) or wet nebulizer on objective measurements of acute airflow obstruction in adult …

We compared two modes of aerosol bronchodilator delivery in 34 patients hospitalized with
obstructive airways diseases. The standard mode, therapist-administered up-draft …

Background: Comparative studies of albuterol by wet nebulizer or metered dose inhaler
have tested fixed doses of medications. We compared the dose-response relationship to …

Background It has been suggested that overuse of fenoterol metered-dose inhalers (MDIs)
may increase the risk of death from asthma due to cardiac arrhythmias. Our primary …

We determined the relative efficacy of two bronchodilator aerosol delivery methods in 18
intubated mechanically ventilated patients with airways obstruction. Two treatment arms …

OBJECTIVE: To critically review the use of beta-adrenergic agonists in acute, severe asthma
with particular focus on aerosol administration. DATA SOURCES: English language articles …

Background Because interpatient variability in bronchodilation from inhaled albuterol is
large and clinically important, we characterized the albuterol dose/response relationship by …

The response to therapeutic aerosols is considered to be a function of the dose deposited at
the target site in the lung. The dose, in turn, is dependent upon the system producing the …