Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia

S Branford, NCP Cross, A Hochhaus, J Radich… - Leukemia, 2006 - nature.com
Molecular monitoring for patients with chronic myeloid leukaemia (CML) has become an
important practice in the era of imatinib therapy. For successful widespread introduction into …

Chronic myeloid leukemia, version 2.2021, NCCN clinical practice guidelines in oncology

MW Deininger, NP Shah, JK Altman, E Berman… - Journal of the National …, 2020 - jnccn.org
Chronic myeloid leukemia (CML) is defined by the presence of Philadelphia chromosome
(Ph) which results from a reciprocal translocation between chromosomes 9 and 22 [t (9; 22] …

Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: practical advice on the use and …

H Kantarjian, C Schiffer, D Jones… - Blood, The Journal of …, 2008 - ashpublications.org
The management of hematologic malignancies, including chronic myeloid leukemia (CML),
chronic lymphocytic leukemia (CLL), and acute lymphocytic leukemia (ALL), has led the way …

Chronic myeloid leukemia, version 1.2019, NCCN clinical practice guidelines in oncology

JP Radich, M Deininger, CN Abboud, JK Altman… - Journal of the National …, 2018 - jnccn.org
Chronic myeloid leukemia (CML) is defined by the presence of Philadelphia chromosome
(Ph), resulting from a reciprocal translocation between chromosomes 9 and 22 [t (9; 22] that …

Dynamics of chronic myeloid leukaemia

F Michor, TP Hughes, Y Iwasa, S Branford, NP Shah… - Nature, 2005 - nature.com
The clinical success of the ABL tyrosine kinase inhibitor imatinib in chronic myeloid
leukaemia (CML) serves as a model for molecularly targeted therapy of cancer,,,, but at least …

[HTML][HTML] Final report of a phase II study of imatinib mesylate with hyper-CVAD for the front-line treatment of adult patients with Philadelphia chromosome-positive acute …

N Daver, D Thomas, F Ravandi, J Cortes, R Garris… - …, 2015 - ncbi.nlm.nih.gov
We have previously reported on the efficacy and tolerability of hyper-CVAD regimen
(cyclophosphamide, vincristine, Adriamycin, and dexamethasone) and imatinib followed by …

Treatment of Philadelphia chromosome–positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate

DA Thomas, S Faderl, J Cortes, S O'Brien, FJ Giles… - Blood, 2004 - ashpublications.org
Imatinib mesylate, an inhibitor of the Bcr-Abl tyrosine kinase, has modest activity in
refractory/relapsed Philadelphia chromosome (Ph)-positive acute lymphocytic leukemia …

Chronic myeloid leukemia, version 2.2024, nccn clinical practice guidelines in oncology

NP Shah, R Bhatia, JK Altman, M Amaya… - Journal of the National …, 2024 - jnccn.org
Chronic myeloid leukemia (CML) is defined by the presence of Philadelphia chromosome
resulting from a reciprocal translocation between chromosomes 9 and 22 [t9; 22] that gives …

High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome–positive chronic phase chronic myeloid leukemia

H Kantarjian, M Talpaz, S O'Brien, G Garcia-Manero… - Blood, 2004 - ashpublications.org
Imatinib mesylate (STI571) is effective in chronic phase chronic myelogenous leukemia
(CML). However, most patients treated with 400 mg imatinib daily have variable levels of …

Complete cytogenetic and molecular responses to interferon‐α‐based therapy for chronic myelogenous leukemia are associated with excellent long‐term prognosis

HM Kantarjian, S O'Brien, JE Cortes… - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND Little is known regarding long‐term prognosis among patients with
Philadelphia chromosome (Ph)‐positive chronic myelogenous leukemia (CML) who achieve …