Clinical and translational research has played a major role in advancing our understanding
of pulmonary hypertension (PH), including pulmonary arterial hypertension and other forms …

Idiopathic pulmonary fibrosis (IPF) is a complex disease of unknown aetiology, which makes
drug development challenging. Single administration of bleomycin directly to the lungs of …

Preregistrations—records made a priori about study designs and analysis plans and placed
in open repositories—are thought to strengthen the credibility and transparency of research …

Respiratory infections are a leading cause of mortality worldwide. Most of the research on
the underlying disease mechanisms is based on cell culture, organoid, or surrogate animal …

This review seeks to provide an update of preclinical findings and available clinical data on
the chronic persistent inflammation and its direct role on the pulmonary arterial hypertension …

Background Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease with few treatment
options. The poor success in developing anti-IPF strategies has impelled researchers to …

Airway and alveolar epithelial cells in culture | European Respiratory Society Skip to main
content Main menu Home Current issue ERJ Early View Past issues ERS Guidelines …

The respiratory epithelium is intimately associated with the pathophysiologies of highly
infectious viral contagions and chronic illnesses such as chronic obstructive pulmonary …

Aims The progressive accumulation of cells in pulmonary vascular walls is a key
pathological feature of pulmonary arterial hypertension (PAH) that results in narrowing of the …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive degenerative lung disease
leading to respiratory failure and death. Although anti-fibrotic drugs are now available for …