The N‐myc downstream regulated gene (NDRG) family of proteins consists of 4 members,
NDRG1–4, which are well conserved through evolution. The first member to be discovered …

N-myc downstream-regulated gene 1 (NDRG1) is an intracellular protein that is induced
under a wide variety of stress and cell growth-regulatory conditions. NDRG1 is up-regulated …

Background Growing evidence has suggested that immune-related genes play crucial roles
in the development and progression of hepatocellular carcinoma (HCC). Nevertheless, the …

Cancer is a leading cause of death worldwide, resulting in∼ 10 million deaths in 2020.
Major oncogenic effectors are the Myc proto-oncogene family, which consists of three …

N-myc down-regulated gene 1 (NDRG1) is a known metastasis suppressor in multiple
cancers, being also involved in embryogenesis and development, cell growth and …

N-myc downstream-regulated gene 1 (NDRG1) has been reported to be a multifunctional
protein associated with carcinogenesis, however, the cellular function of NDRG1 remains …

Iron is essential for normal cellular function. It participates in a wide variety of cellular
processes, including cellular respiration, DNA synthesis, and macromolecule biosynthesis …

The molecular mechanisms and genetic programs required for cancer metastasis are
sometimes overlapping, but components are clearly distinct from those promoting growth of …

Simple Summary NDRG1 (N-myc downregulated gene-1) has been reported to suppress
metastasis, to be a biomarker of poor outcome, and to be a facilitator of disease progression …

The major problem for cancer patients is metastasis of the cancer from the primary tumor to
secondary sites. Metastasis is the process by which tumor cells disseminate from the primary …