Drugs with anticholinergic properties and cognitive performance in the elderly: results from the PAQUID Study

N Lechevallier‐Michel, M Molimard… - British journal of …, 2005 - Wiley Online Library
Objectives To measure the association between the use of drugs with anticholinergic
properties and cognitive performance in an elderly population, the PAQUID cohort. Methods …

Clinical consequences of polypharmacy in elderly: expect the unexpected, think the unthinkable

JA Salazar, I Poon, M Nair - Expert opinion on drug safety, 2007 - Taylor & Francis
Multiple medication use has been coined 'polypharmacy'. Polypharmacy is highly prevalent
in older patients secondary to the increased number of co-morbid disease states with …

Assessing the scope and appropriateness of prescribing cascades

LM McCarthy, JD Visentin… - Journal of the American …, 2019 - Wiley Online Library
As originally defined, the term “prescribing cascade” describes a sequence of events that
begins when an adverse drug event (ADE) occurs, is misinterpreted as a new medical …

Cognitive impairment, drug use, and the risk of hip fracture in persons over 75 years old: a community-based prospective study

Z Guo, P Wills, M Viitanen, J Fastbom… - American Journal of …, 1998 - academic.oup.com
The authors examined the effects of cognitive function, as assessed by the Mini-Mental State
Examination, and drug use on the incidence of hip fracture in a community-based Swedish …

Atypical antipsychotics and parkinsonism

PA Rochon, TA Stukel, K Sykora, S Gill… - Archives of internal …, 2005 - jamanetwork.com
Background Atypical antipsychotic agents are thought to be less likely than older typical
agents to produce parkinsonism. This has not been well documented. We compared the risk …

[PDF][PDF] The prescribing cascade

LM Kalisch, GE Caughey, EE Roughead… - Australian Prescriber, 2011 - nps.org.au
A prescribing cascade occurs when a new medicine is prescribed to'treat'an adverse
reaction to another drug in the mistaken belief that a new medical condition requiring …

Use of anticholinergic medications by older adults with dementia

CM Roe, MJ Anderson… - Journal of the American …, 2002 - Wiley Online Library
OBJECTIVES: To compare the prevalence of anticholinergic use in older adults with
probable dementia with that of a matched comparison group of older adults who were …

ThinkCascades: a tool for identifying clinically important prescribing cascades affecting older people

LM McCarthy, R Savage, K Dalton, R Mason, J Li… - Drugs & aging, 2022 - Springer
Abstract Background and Objective Prescribing cascades occur when a drug is prescribed
to manage side effects of another drug, typically when a side effect is misinterpreted as a …

What is known about preventing, detecting, and reversing prescribing cascades: a scoping review

H Brath, N Mehta, RD Savage, SS Gill… - Journal of the …, 2018 - Wiley Online Library
OBJECTIVES To systematically describe the resources available on preventing, detecting,
and reversing prescribing cascades using a scoping review methodology …

Prescribing cascades with recommendations to prevent or reverse them: a systematic review

O Adrien, AK Mohammad, JG Hugtenburg… - Drugs & Aging, 2023 - Springer
Background To reduce prescribing cascades occurring in clinical practice, healthcare
providers require information on the prescribing cascades they can recognize and prevent …