The understanding of deposition of particles in the respiratory tract is of great value to risk
assessment of inhalation toxicology and to improve efficiency in drug delivery of inhalation …

Delivery of therapeutic agents via the pulmonary route has gained significant attention over
the past few decades because this route of administration offers multiple advantages over …

Recent developments in the prediction of local aerosol deposition in human lungs are driven
by the fast development of computational simulations. Although such simulations provide …

This article is part of a series of reports from the “Orlando Inhalation Conference-Approaches
in International Regulation” which was held in March 2014, and coorganized by the …

To understand the determinants of inhaled aerosol particle distribution and targeting in the
lung, knowledge of regional deposition, lung morphology and regional ventilation, is crucial …

This article reviews the pulmonary route of administration, aerosol delivery devices,
characterization of pulmonary drug delivery systems, and discusses the rationale for inhaled …

This review will cover the principles of imaging the deposition of inhaled drugs and some of
the state-of-the art imaging techniques being used today. Aerosol deposition can be imaged …

Deposition and clearance studies are used during product development and in fundamental
research. These studies mostly involve radionuclide imaging, but pharmacokinetic methods …

Particulate matter (PM) in dust causes serious pathological conditions, and it has been
considered a critical health issue for many years. Respiratory disorders such as bronchitis …

Background: While it is generally accepted that inertial impaction will lead to particle loss as
aerosol is being carried into the pulmonary airways, most predictive aerosol deposition …