Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative
disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of …

Although previously restricted to a limited number of medical conditions, there is a growing
appreciation that 'autoimmune'(or immune-mediated) processes are important aspects of a …

Liposomes modified with tetradecyltriphenylphosphonium bromide with dual loading of α-
tocopherol and donepezil hydrochloride were successfully designed for intranasal …

Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …

The changes in the properties of three biological events that occur with cerebral aging are
discussed. These adverse changes already begin to develop early in mid-life and gradually …

Mitochondrial dysfunction has been implicated in the pathogenesis of Alzheimer's disease, a
neurodegenerative disorder characterized by progressive cognitive decline. Voltage …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive decline, memory loss, and impaired daily functioning. While there is currently no …

Oleoylethanolamide (OEA) is an endogenous lipid mediator which is being discussed as a
weight-loss drug for obesity. In addition to its homoeostatic functions, OEA has …

In this paper we use simulation methods to study a hypothetical uncoupling agent as a
therapy for dementia. We simulate the proliferation of mitochondrial deletion mutants …

The changes in the properties of three biological events, that occur with cerebral aging, are
discussed. These adverse changes already begin to develop early in mid-life and gradually …