[HTML][HTML] Advances in tissue engineering and innovative fabrication techniques for 3-D-structures: translational applications in neurodegenerative diseases
F Rey, B Barzaghini, A Nardini, M Bordoni, GV Zuccotti… - Cells, 2020 - mdpi.com
In the field of regenerative medicine applied to neurodegenerative diseases, one of the most
important challenges is the obtainment of innovative scaffolds aimed at improving the …
important challenges is the obtainment of innovative scaffolds aimed at improving the …
[HTML][HTML] Fostering mesenchymal stem cell therapy to halt cytokine storm in COVID-19
M Jeyaraman, A John, S Koshy, R Ranjan… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) has been threatening the globe since
the end of November 2019. The disease revealed cracks in the health care system as health …
the end of November 2019. The disease revealed cracks in the health care system as health …
[HTML][HTML] Neurofilament accumulations in amyotrophic lateral sclerosis patients' motor neurons impair axonal initial segment integrity
C Lefebvre-Omar, E Liu, C Dalle, BL d'Incamps… - Cellular and Molecular …, 2023 - Springer
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron (MN) disease in
adults with no curative treatment. Neurofilament (NF) level in patient'fluids have recently …
adults with no curative treatment. Neurofilament (NF) level in patient'fluids have recently …
[HTML][HTML] Umbilical cord mesenchymal stem cells in amyotrophic lateral sclerosis: an original study
M Barczewska, S Maksymowicz… - Stem Cell Reviews and …, 2020 - Springer
Objective Amyotrophic lateral sclerosis (ALS) is still incurable. Although different therapies
can affect the health and survival of patients. Our aim is to evaluate the effect of umbilical …
can affect the health and survival of patients. Our aim is to evaluate the effect of umbilical …
[HTML][HTML] Expression of endogenous angiotensin-converting enzyme 2 in human induced pluripotent stem cell-derived retinal organoids
HI Ahmad Mulyadi Lai, SJ Chou, Y Chien… - International Journal of …, 2021 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2) was identified as the main host cell receptor for
the entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its …
the entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its …
[HTML][HTML] Mini-Review: Induced pluripotent stem cells and the search for new cell-specific ALS therapeutic targets
L Ferraiuolo, NJ Maragakis - Neuroscience letters, 2021 - Elsevier
Amongst the most important discoveries in ALS pathobiology are the works demonstrating
that multiple cell types contribute to disease onset and progression. However, a significant …
that multiple cell types contribute to disease onset and progression. However, a significant …
[HTML][HTML] Organ on a Chip: A Novel in vitro Biomimetic Strategy in Amyotrophic Lateral Sclerosis (ALS) Modeling
B Arjmand, S Kokabi Hamidpour, Z Rabbani… - Frontiers in …, 2022 - frontiersin.org
Amyotrophic lateral sclerosis is a pernicious neurodegenerative disorder that is associated
with the progressive degeneration of motor neurons, the disruption of impulse transmission …
with the progressive degeneration of motor neurons, the disruption of impulse transmission …
[HTML][HTML] Leveraging microphysiological systems to address challenges encountered during development of oligonucleotide therapeutics
Oligonucleotide therapeutics (ONTs) encompass classes of medicines that selectively target
and potentially ameliorate previously untreatable and often rare diseases. Several unique …
and potentially ameliorate previously untreatable and often rare diseases. Several unique …
Small molecules targeting different cellular pathologies for the treatment of amyotrophic lateral sclerosis
MF Elmansy, CT Reidl, M Rahaman… - Medicinal Research …, 2023 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease in which the
motor neuron circuitry displays progressive degeneration, affecting mostly the motor …
motor neuron circuitry displays progressive degeneration, affecting mostly the motor …
[HTML][HTML] In vitro 3D modeling of neurodegenerative diseases
A Louit, T Galbraith, F Berthod - Bioengineering, 2023 - mdpi.com
The study of neurodegenerative diseases (such as Alzheimer's disease, Parkinson's
disease, Huntington's disease, or amyotrophic lateral sclerosis) is very complex due to the …
disease, Huntington's disease, or amyotrophic lateral sclerosis) is very complex due to the …