New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity

M Furuhashi - American Journal of Physiology …, 2020 - journals.physiology.org
Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase
and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from …

Sex differences in urate handling

VL Halperin Kuhns, OM Woodward - International journal of molecular …, 2020 - mdpi.com
Hyperuricemia, or elevated serum urate, causes urate kidney stones and gout and also
increases the incidence of many other conditions including renal disease, cardiovascular …

Limosilactobacillus fermentum JL-3 isolated from “Jiangshui” ameliorates hyperuricemia by degrading uric acid

Y Wu, Z Ye, P Feng, R Li, X Chen, X Tian, R Han… - Gut …, 2021 - Taylor & Francis
Recent studies into the beneficial effects of fermented foods have shown that this class of
foods are effective in managing hyperuricemia and gout. In this study, the uric acid (UA) …

The prevalence of hyperuricemia and its correlates among adults in China: results from CNHS 2015–2017

W Piao, L Zhao, Y Yang, H Fang, L Ju, S Cai, D Yu - Nutrients, 2022 - mdpi.com
This study aimed to investigate the prevalence of hyperuricemia (HUA) and associated risk
factors in Chinese adults aged 18 to 59 years. All the data were collected from the China …

Adherence to the dietary approaches to stop hypertension diet and hyperuricemia: a cross‐sectional study

Y Gao, L Cui, Y Sun, W Yang, J Wang… - Arthritis Care & …, 2021 - Wiley Online Library
Objective Although several individual nutrients/foods are associated with uric acid status, the
association of overall diet quality with hyperuricemia remains unclear. The current study was …

Molecular pathophysiology of uric acid homeostasis

C Estiverne, AK Mandal, DB Mount - Seminars in nephrology, 2020 - Elsevier
Uric acid, the end product of purine metabolism, plays a key role in the pathogenesis of gout
and other disease processes. The circulating serum uric acid concentration is governed by …

The role of uric acid in preeclampsia: is uric acid a causative factor or a sign of preeclampsia?

OP Khaliq, T Konoshita, J Moodley… - Current hypertension …, 2018 - Springer
Abstract Purpose of Review Because of the significant discrepancies on this topic, this
review will focus on the role of uric acid in PE, uric acid as a predictor of preeclampsia and …

[PDF][PDF] Association between serum uric acid and non-alcoholic fatty liver disease: a meta-analysis

G Darmawan, L Hamijoyo, I Hasan - Acta Med Indones, 2017 - researchgate.net
Background: non-alcoholic fatty liver disease (NAFLD) is known to be associated with some
metabolic disorders. Recent studies suggested the role of uric acid in NAFLD through …

Association between the prevalence of hyperuricemia and reproductive hormones in polycystic ovary syndrome

L Mu, J Pan, L Yang, Q Chen, Y Chen, Y Teng… - Reproductive Biology …, 2018 - Springer
Background The prevalecne of hyperuricemia in polycystic ovary syndrome (PCOS) is still
uncertain. We aimed to investigate the prevalence of hyperuricemia in PCOS and to …

Hyperuricemia and endothelial function: is it a simple association or do gender differences play a role in this binomial?

T Ciarambino, P Crispino, M Giordano - Biomedicines, 2022 - mdpi.com
The endothelium plays a fundamental role in the biological processes that ensure
physiological vessel integrity, synthesizing numerous substances that are capable of …