Heterogeneity and plasticity of epithelial–mesenchymal transition (EMT) in cancer metastasis: Focusing on partial EMT and regulatory mechanisms
D Li, L Xia, P Huang, Z Wang, Q Guo, C Huang… - Cell …, 2023 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) or mesenchymal–epithelial transition (MET) plays
critical roles in cancer metastasis. Recent studies, especially those based on single‐cell …
critical roles in cancer metastasis. Recent studies, especially those based on single‐cell …
[HTML][HTML] Circulating tumor cells as predictive and prognostic biomarkers in solid tumors
M Capuozzo, F Ferrara, M Santorsola, A Zovi… - Cells, 2023 - mdpi.com
Circulating tumor cells (CTCs) have emerged as pivotal biomarkers with significant
predictive and prognostic implications in solid tumors. Their presence in peripheral blood …
predictive and prognostic implications in solid tumors. Their presence in peripheral blood …
[HTML][HTML] Epithelial–mesenchymal transition (EMT) 2021
G Manfioletti, M Fedele - International journal of molecular sciences, 2022 - mdpi.com
Epithelial–mesenchymal transition (EMT) is a transdifferentiation process wherein epithelial
cells acquire characteristics typical of mesenchymal cells. In this dynamic and reversible …
cells acquire characteristics typical of mesenchymal cells. In this dynamic and reversible …
[HTML][HTML] TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Q Ping, C Wang, X Cheng, Y Zhong, R Yan… - Journal of Translational …, 2023 - Springer
Background Bladder cancer is one of the most common malignant tumors of the urinary
system and is associated with a poor prognosis once invasion and distant metastases occur …
system and is associated with a poor prognosis once invasion and distant metastases occur …
Melatonin modulates tumor metabolism and mitigates metastasis
Introduction Melatonin, originally isolated from the mammalian pineal gland, was
subsequently identified in many animal cell types and in plants. While melatonin was …
subsequently identified in many animal cell types and in plants. While melatonin was …
Metabolic remodeling in cancer and senescence and its therapeutic implications
Y Kim, Y Jang, MS Kim, C Kang - Trends in Endocrinology & Metabolism, 2024 - cell.com
Cellular metabolism is a flexible and plastic network that often dictates physiological and
pathological states of the cell, including differentiation, cancer, and aging. Recent advances …
pathological states of the cell, including differentiation, cancer, and aging. Recent advances …
[HTML][HTML] Progress of tumor-associated macrophages in the epithelial-mesenchymal transition of tumor
X Li, L Chen, X Peng, X Zhan - Frontiers in Oncology, 2022 - frontiersin.org
As a significant public health problem with high morbidity and mortality worldwide, tumor is
one of the major diseases endangering human life. Moreover, metastasis is the most …
one of the major diseases endangering human life. Moreover, metastasis is the most …
[HTML][HTML] Recent Advances in Transcription Factors Biomarkers and Targeted Therapies Focusing on Epithelial–Mesenchymal Transition
KT Chuang, SS Chiou, SH Hsu - Cancers, 2023 - mdpi.com
Simple Summary The study discusses the potential of targeting transcription factors (TFs) for
cancer therapy and provide a systematic classification of various types of TFs involved in the …
cancer therapy and provide a systematic classification of various types of TFs involved in the …
RBM10 recruits METTL3 to induce N6-methyladenosine-MALAT1-dependent modification, inhibiting the invasion and migration of NSCLC
Y Cao, X Di, S Cong, C Tian, Y Wang, X Jin, M Zhao… - Life Sciences, 2023 - Elsevier
Aims Previous studies have shown that RNA binding motif 10 (RBM10) is a potential tumor
suppressor protein that can inhibit proliferation and promote apoptosis of non-small cell lung …
suppressor protein that can inhibit proliferation and promote apoptosis of non-small cell lung …
[HTML][HTML] Functional interplay between long non-coding RNAs and Breast CSCs
Breast cancer (BC) represents aggressive cancer affecting most women's lives globally.
Metastasis and recurrence are the two most common factors in a breast cancer patient's …
Metastasis and recurrence are the two most common factors in a breast cancer patient's …