[HTML][HTML] EAAT2 as a therapeutic research target in Alzheimer's disease: A systematic review
OWG Wood, JHY Yeung, RLM Faull… - Frontiers in …, 2022 - frontiersin.org
Glutamate is the main excitatory neurotransmitter in the human central nervous system,
responsible for a wide variety of normal physiological processes. Glutamatergic metabolism …
responsible for a wide variety of normal physiological processes. Glutamatergic metabolism …
Proteinopathies: deciphering physiology and mechanisms to develop effective therapies for neurodegenerative diseases
Neurodegenerative diseases (NDs) are a cluster of diseases marked by progressive
neuronal loss, axonal transport blockage, mitochondrial dysfunction, oxidative stress …
neuronal loss, axonal transport blockage, mitochondrial dysfunction, oxidative stress …
Efficacy and tolerability of olive oil-based ketogenic diet in children with drug-resistant epilepsy: A single center experience from Turkey
O Guzel, U Uysal, N Arslan - european journal of paediatric neurology, 2019 - Elsevier
Purpose Ketogenic diet (KD) is an effective non-pharmacological treatment for drug-resistant
epilepsy. The aim of this study was to investigate the efficacy, tolerability and complications …
epilepsy. The aim of this study was to investigate the efficacy, tolerability and complications …
Novel olive oil phenolic (−)-oleocanthal (+)-xylitol-based solid dispersion formulations with potent oral anti-breast cancer activities
Epidemiological studies have compellingly documented the ability of the Mediterranean diet
rich in extra-virgin olive oil to reduce the incidence of certain malignancies, and …
rich in extra-virgin olive oil to reduce the incidence of certain malignancies, and …
Role of the ketogenic diet in acute neurological diseases
The current review outlines the role of ketogenic diet (KD) in the management of acute
neurological conditions namely traumatic brain injury, ischemic stroke, status epilepticus …
neurological conditions namely traumatic brain injury, ischemic stroke, status epilepticus …
[HTML][HTML] Does diet have a role in the treatment of Alzheimer's disease?
M Thelen, HM Brown-Borg - Frontiers in aging neuroscience, 2020 - frontiersin.org
The aging process causes many changes to the brain and is a major risk factor for the
development of neurodegenerative diseases such as Alzheimer's Disease (AD). Despite an …
development of neurodegenerative diseases such as Alzheimer's Disease (AD). Despite an …
Upregulation of thioredoxin-interacting protein in brain of amyloid-β protein precursor/presenilin 1 transgenic mice and amyloid-β treated neuronal cells
Y Wang, Y Wang, V Bharti, H Zhou… - Journal of …, 2019 - content.iospress.com
Oxidative stress has been hypothesized to play a role in the pathophysiology of Alzheimer's
disease (AD). Previously, we found that total nitrosylated protein levels were increased in …
disease (AD). Previously, we found that total nitrosylated protein levels were increased in …
Natural molecules for healthy lifestyles: Oleocanthal from extra virgin olive oil
V Francisco, C Ruiz-Fernández, V Lahera… - Journal of agricultural …, 2019 - ACS Publications
Extra virgin olive oil (EVOO) is the main source of fat in the Mediterranean diet. Phenolic
compounds of EVOO, in particular, secoiridoids, are minor components that have generated …
compounds of EVOO, in particular, secoiridoids, are minor components that have generated …
[HTML][HTML] (−)-Oleocanthal prevents breast cancer locoregional recurrence after primary tumor surgical excision and neoadjuvant targeted therapy in orthotopic nude …
Breast cancer (BC) recurrence represents a challenge for survivors who have had their
primary tumors surgically excised, and/or have completed radiation, neoadjuvant, or …
primary tumors surgically excised, and/or have completed radiation, neoadjuvant, or …
Glutamate metabolism in mitochondria is closely related to alzheimer's disease
J Song, X Yang, M Zhang, C Wang… - Journal of Alzheimer's …, 2021 - content.iospress.com
Glutamate is the main excitatory neurotransmitter in the brain, and its excitatory neurotoxicity
is closely related to the occurrence and development of Alzheimer's disease. However …
is closely related to the occurrence and development of Alzheimer's disease. However …