Pathogenesis of allergic diseases and implications for therapeutic interventions

J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

Type 2 immunity in the skin and lungs

CA Akdis, PD Arkwright, MC Brüggen, W Busse… - Allergy, 2020 - Wiley Online Library
There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …

Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

H Breiteneder, YQ Peng, I Agache, Z Diamant… - Allergy, 2020 - Wiley Online Library
Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

Advances and novel developments in allergic rhinitis

Y Meng, C Wang, L Zhang - Allergy, 2020 - Wiley Online Library
Allergic rhinitis (AR) is an upper airway disease with high prevalence in the world, and
therefore needs to be thoroughly investigated and treated accordingly. Although the …

The role of Treg cell subsets in allergic disease

T Boonpiyathad, ZC Sözener, M Akdis… - Asian Pacific journal of …, 2020 - zora.uzh.ch
Allergic diseases are caused by a hypersensitivity reaction to an external substance that is
normally not harmful to the body. An imbalance between type 2 immune response and …

Quercetin improves the imbalance of Th1/Th2 cells and Treg/Th17 cells to attenuate allergic rhinitis

X Ke, Z Chen, X Wang, H Kang, S Hong - Autoimmunity, 2023 - Taylor & Francis
Allergic rhinitis (AR) is a common inflammation that affects many people globally. Quercetin
has anti-allergic biological activity in AR. Here, we aimed to explore the effects of quercetin …

MIR222HG attenuates macrophage M2 polarization and allergic inflammation in allergic rhinitis by targeting the miR146a-5p/TRAF6/NF-κB axis

S Wen, F Li, Y Tang, L Dong, Y He, Y Deng… - Frontiers in …, 2023 - frontiersin.org
Although M2 macrophages are involved in the orchestration of type 2 inflammation in
allergic diseases, the mechanisms underlying non-coding RNA (ncRNA)-mediated …

Immunomodulatory properties of mesenchymal stem cells: A potential therapeutic strategy for allergic rhinitis

M Wang, N Zhao, C Wang, ZB Jin, L Zhang - Allergy, 2023 - Wiley Online Library
Allergic rhinitis is a highly prevalent chronic inflammatory disorder of the nasal mucosa that
poses a significant burden on patients' health and quality of life. Current therapies for …

Association between air pollution and outpatient visits for allergic rhinitis: Effect modification by ambient temperature and relative humidity

R Wu, Q Guo, J Fan, C Guo, G Wang, W Wu… - Science of The Total …, 2022 - Elsevier
Mounting evidence indicated the associations between air pollution and outpatient visits for
allergic rhinitis (AR), while few studies assessed the effect modification of these associations …

Association between microbiota and nasal mucosal diseases in terms of immunity

J Tai, MS Han, J Kwak, TH Kim - International journal of molecular …, 2021 - mdpi.com
The pathogenesis of nasal inflammatory diseases is related to various factors such as
anatomical structure, heredity, and environment. The nasal microbiota play a key role in …