The objective of this study was to evaluate the protective immunity of excretory-secretory
products of Fasciola hepatica (FhES) worm against S. mansoni infection in mice. Evaluation …

The fear that schistosomes will become resistant to praziquantel (PZQ) motivates the search
for alternatives to treat schistosomiasis. The antimalarials quinine (QN) and halofantrine …

The level of drug-metabolizing enzymes (cytochrome P450 [CYP450] and cytochrome b5
[cyt b5]) and the bioavailability of praziquantel (PZQ) were investigated in batches of mice …

This study was designed to evaluate the potential Schistosomacidal action of Nigella sativa
(N. sativa) crushed seeds in mice experimentally infected with Schistosoma mansoni (S …

A major category of mutant hematopoietic phenotypes in Drosophila is melanotic tumors or
nodules, which consist of abnormal and overproliferated blood cells, similar to granulomas …

Praziquantel (PZQ), the drug of choice according to the World Health Organization (WHO),
causes some side effects. The appearance of drug resistance against PZQ in Schistosoma …

Objectives• Provide a comprehensive overview of the clinical interactions of grapefruit or
other fruit juices with medications to cause altered pharmacokinetics and potential clinical …

Development of antimalarial treatment capable of providing a permanent cure for malaria
has been a herculean task for drug researchers. A trial of a novel, proprietary blend …

Purpose Combination chemotherapy of schistosomiasis mansoni has been studied
previously, with praziquantel being the basis of combination. Artemether and myrrh are …

This study was carried out to evaluate the effect of drug treatments and enzymes level on the
worm burden in an experimental Schistosoma haematobium infected guinea pig. Eggs of S …