Isolated rapid eye movement sleep behavior disorder (iRBD) is a harbinger for developing
clinical synucleinopathies. Magnetic resonance imaging (MRI) has been suggested as a tool …

Identification of reliable biomarkers of prognosis in subjects with high risk to psychosis is an
essential step to improve care and treatment of this population of help-seekers. Longitudinal …

The thalamus is a vital communication hub in the center of the brain and consists of distinct
nuclei critical for consciousness and higher-order cortical functions. Structural and functional …

Transcranial brain stimulation (TBS) has been established as a method for modulating and
mapping the function of the human brain, and as a potential treatment tool in several brain …

Manual segmentation of stacks of 2D biomedical images (eg, histology) is a time-consuming
task which can be sped up with semi-automated techniques. In this article, we present a …

Temporal lobe studies in motor neuron disease overwhelmingly focus on white matter
alterations and cortical grey matter atrophy. Reports on amygdala involvement are …

Objectives To develop an automatic method for accurate and robust thalamus segmentation
in T1w-MRI for widespread clinical use without the need for strict harmonization of …

Background Studies have previously shown evidence for presymptomatic cortical atrophy in
genetic FTD. Whilst initial investigations have also identified early deep grey matter volume …

The thalamic nuclei are involved in many neurodegenerative diseases and therefore, their
identification is of key importance in numerous clinical treatments. Automated segmentation …

The thalamus is a key cerebral hub relaying a multitude of corticoefferent and corticoafferent
connections and mediating distinct extrapyramidal, sensory, cognitive and behavioural …