[HTML][HTML] The genetic architecture of the human thalamus and its overlap with ten common brain disorders
T Elvsåshagen, A Shadrin, O Frei… - Nature …, 2021 - nature.com
The thalamus is a vital communication hub in the center of the brain and consists of distinct
nuclei critical for consciousness and higher-order cortical functions. Structural and functional …
nuclei critical for consciousness and higher-order cortical functions. Structural and functional …
[HTML][HTML] Thalamic nuclei atrophy at high and heterogenous rates during cognitively unimpaired human aging
The thalamus is a central integration structure in the brain, receiving and distributing
information among the cerebral cortex, subcortical structures, and the peripheral nervous …
information among the cerebral cortex, subcortical structures, and the peripheral nervous …
[HTML][HTML] “Switchboard” malfunction in motor neuron diseases: Selective pathology of thalamic nuclei in amyotrophic lateral sclerosis and primary lateral sclerosis
RH Chipika, E Finegan, SLH Shing, MC McKenna… - NeuroImage: Clinical, 2020 - Elsevier
The thalamus is a key cerebral hub relaying a multitude of corticoefferent and corticoafferent
connections and mediating distinct extrapyramidal, sensory, cognitive and behavioural …
connections and mediating distinct extrapyramidal, sensory, cognitive and behavioural …
[HTML][HTML] Differential early subcortical involvement in genetic FTD within the GENFI cohort
M Bocchetta, EG Todd, G Peakman, DM Cash… - NeuroImage: Clinical, 2021 - Elsevier
Background Studies have previously shown evidence for presymptomatic cortical atrophy in
genetic FTD. Whilst initial investigations have also identified early deep grey matter volume …
genetic FTD. Whilst initial investigations have also identified early deep grey matter volume …
Temporal sensitivity for achromatic and chromatic flicker across the visual cortex
The retinal ganglion cells (RGCs) receive different combinations of L, M, and S cone inputs
and give rise to one achromatic and two chromatic postreceptoral channels. The goal of the …
and give rise to one achromatic and two chromatic postreceptoral channels. The goal of the …
[HTML][HTML] In vivo high-resolution structural MRI-based atlas of human thalamic nuclei
Thalamic nuclei play critical roles in regulation of neurological functions like sleep and
wakefulness. They are increasingly implicated in neurodegenerative and neurological …
wakefulness. They are increasingly implicated in neurodegenerative and neurological …
[HTML][HTML] Automatic segmentation of the thalamus using a massively trained 3D convolutional neural network: higher sensitivity for the detection of reduced thalamus …
Objectives To develop an automatic method for accurate and robust thalamus segmentation
in T1w-MRI for widespread clinical use without the need for strict harmonization of …
in T1w-MRI for widespread clinical use without the need for strict harmonization of …
[HTML][HTML] Presymptomatic grey matter alterations in ALS kindreds: a computational neuroimaging study of asymptomatic C9orf72 and SOD1 mutation carriers
Background The characterisation of presymptomatic disease-burden patterns in
asymptomatic mutation carriers has a dual academic and clinical relevance. The …
asymptomatic mutation carriers has a dual academic and clinical relevance. The …
[HTML][HTML] Evolution of human brain atlases in terms of content, applications, functionality, and availability
WL Nowinski - Neuroinformatics, 2021 - Springer
Human brain atlases have been evolving tremendously, propelled recently by brain big
projects, and driven by sophisticated imaging techniques, advanced brain mapping …
projects, and driven by sophisticated imaging techniques, advanced brain mapping …
Thalamic nuclei in frontotemporal dementia: Mediodorsal nucleus involvement is universal but pulvinar atrophy is unique to C9orf72
M Bocchetta, JE Iglesias, M Neason… - Human Brain …, 2020 - Wiley Online Library
Thalamic atrophy is a common feature across all forms of FTD but little is known about
specific nuclei involvement. We aimed to investigate in vivo atrophy of the thalamic nuclei …
specific nuclei involvement. We aimed to investigate in vivo atrophy of the thalamic nuclei …