Patients with childhood, adolescent, and young adult cancer who will be treated with
gonadotoxic therapies are at increased risk for infertility. Many patients and their families …

BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …

Progress in therapy has made survival into adulthood a reality for most children,
adolescents, and young adults with a cancer diagnosis today. Notably, this growing …

The germline cells are essential for the propagation of human beings, thus essential for the
survival of mankind. The germline stem cells, as a unique cell type, generate various states …

Assisted reproductive technologies (ART) are not yet systematically available to people with
sickle cell disease or their parents. Fertility care for these groups requires addressing sickle …

Patient survival following childhood cancer has increased with contemporary radiation and
chemotherapy techniques. However, gonadotoxicity associated with treatments means that …

Simple Summary The following review addresses the effects of cancer and cancer
treatments on fertility and reproductive health, and reviews standard and novel fertility …

Abstract Purpose of Review Although fertility preservation is not yet fully integrated into the
comprehensive cancer care of pediatric and adolescent patients, advances continue to take …

Discussions regarding gonadal function and possible disease or treatment-related ovarian
or testicular dysfunction, sexual dysfunction, and possible future infertility can be challenging …

PURPOSE: Fertility discussions are an integral part of comprehensive care for pediatric,
adolescent, and young adult patients newly diagnosed with cancer and are supported by …