[HTML][HTML] Wuhan to world: the COVID-19 pandemic

A Kumar, R Singh, J Kaur, S Pandey… - Frontiers in cellular …, 2021 - frontiersin.org
COVID-19 is a Severe Acute Respiratory Syndrome (SARS), caused by SARS-CoV-2, a
novel virus which belongs to the family Coronaviridae. It was first reported in December …

The emerging SARS-CoV-2 variants of concern

A Sanyaolu, C Okorie, A Marinkovic… - Therapeutic …, 2021 - journals.sagepub.com
Since emerging from Wuhan, China, in December of 2019, the coronavirus (SARS-CoV-2)
has been causing devastating severe respiratory infections in humans worldwide. With the …

Structural impact on SARS-CoV-2 spike protein by D614G substitution

J Zhang, Y Cai, T Xiao, J Lu, H Peng, SM Sterling… - Science, 2021 - science.org
Substitution for aspartic acid (D) by glycine (G) at position 614 in the spike (S) protein of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears to facilitate rapid …

[PDF][PDF] Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity

E Volz, V Hill, JT McCrone, A Price, D Jorgensen… - Cell, 2021 - cell.com
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G
are suggestive of a selective advantage but may also be due to a random founder effect. We …

Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2

A Popa, JW Genger, MD Nicholson, T Penz… - Science translational …, 2020 - science.org
Superspreading events shaped the coronavirus disease 2019 (COVID-19) pandemic, and
their rapid identification and containment are essential for disease control. Here, we provide …

[HTML][HTML] Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies

M Yuan, H Liu, NC Wu, IA Wilson - Biochemical and biophysical research …, 2021 - Elsevier
Immediately from the outset of the COVID-19 pandemic, researchers from diverse
biomedical and biological disciplines have united to study the novel pandemic virus, SARS …

Molecular architecture of early dissemination and massive second wave of the SARS-CoV-2 virus in a major metropolitan area

SW Long, RJ Olsen, PA Christensen, DW Bernard… - MBio, 2020 - Am Soc Microbiol
We sequenced the genomes of 5,085 severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strains causing two coronavirus disease 2019 (COVID-19) disease waves in …

The D614G mutations in the SARS-CoV-2 spike protein: Implications for viral infectivity, disease severity and vaccine design

DC Groves, SL Rowland-Jones, A Angyal - Biochemical and biophysical …, 2021 - Elsevier
The development of the SARS-CoV-2 pandemic has prompted an extensive worldwide
sequencing effort to characterise the geographical spread and molecular evolution of the …

Evolution of SARS-CoV-2: review of mutations, role of the host immune system

H Banoun - Nephron, 2021 - karger.com
Since the reporting of the first cases of coronavirus in China and the publication of the first
sequence of SARS-CoV-2 in December 2019, the virus has undergone numerous …

Functional importance of the D614G mutation in the SARS-CoV-2 spike protein

CB Jackson, L Zhang, M Farzan, H Choe - Biochemical and Biophysical …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped virus
which binds its cellular receptor angiotensin-converting enzyme 2 (ACE2) and enters hosts …