Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively
affects survivals' functional outcome, response to rehabilitation and quality of life …

Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …

Treatment‐resistant depression (TRD) is common and associated with multiple serious
public health implications. A consensus definition of TRD with demonstrated predictive utility …

Background Conventional meta-analyses have shown inconsistent results for efficacy of
second-generation antidepressants. We therefore did a multiple-treatments meta-analysis …

It is becoming increasingly apparent that probiotics are important to the health of the host.
The absence of probiotic bacteria in the gut can have adverse effects not only locally in the …

Depression is one of the most common psychological diseases with significant potential
morbidity and mortality. Although the underlying pathophysiology of depression has not …

A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Major depressive disorder (MDD) is a chronic, recurring, and debilitating mental illness that
is the most common mood disorder in the United States. It has been almost 50 years since …

The synthesis and structure− activity relationship of a novel series of compounds with
combined effects on 5-HT3A and 5-HT1A receptors and on the serotonin (5-HT) transporter …

Current management of major depression, a common and debilitating disorder with a high
social and personal cost, is far from satisfactory. All available antidepressants act through …