The connection between tricarboxylic acid cycle enzyme mutations and pseudohypoxic signaling in pheochromocytoma and paraganglioma
Y Wang, B Liu, F Li, Y Zhang, X Gao, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors
originating from chromaffin cells, holding significant clinical importance due to their capacity …
originating from chromaffin cells, holding significant clinical importance due to their capacity …
The Immune Landscape of Pheochromocytoma and Paraganglioma: Current Advances and Perspectives
O Uher, K Hadrava Vanova, D Taïeb… - Endocrine …, 2024 - academic.oup.com
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors derived
from neural crest cells from adrenal medullary chromaffin tissues or extra-adrenal …
from neural crest cells from adrenal medullary chromaffin tissues or extra-adrenal …
Fluorescence-guided minimally-invasive resection of abdominal paragangliomas using indocyanine green
MA van Dam, A Crobach, B Boekestijn… - Scientific Reports, 2024 - nature.com
This retrospective study explores the utility of near-infrared (NIR) fluorescence imaging with
indocyanine green (ICG) in enhancing the intraoperative identification and guidance for the …
indocyanine green (ICG) in enhancing the intraoperative identification and guidance for the …
Current prospects of hereditary adrenal tumors: towards better clinical management
A Ohmoto, N Hayashi, S Takahashi, A Ueki - Hereditary Cancer in Clinical …, 2024 - Springer
Adrenocortical carcinoma (ACC) and pheochromocytoma/paraganglioma (PPGL) are two
rare types of adrenal gland malignancies. Regarding hereditary tumors, some patients with …
rare types of adrenal gland malignancies. Regarding hereditary tumors, some patients with …
Clinical and molecular markers guide the genetics of pheochromocytoma and paraganglioma
A Cascón, M Robledo - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Over the past two decades, research into the genetic susceptibility behind
pheochromocytoma and paraganglioma (PPGL) has surged, ranking them among the most …
pheochromocytoma and paraganglioma (PPGL) has surged, ranking them among the most …
Metabolomic profile of neuroendocrine tumors identifies methionine, porphyrin, and tryptophan metabolisms as key dysregulated pathways associated with patient …
A La Salvia, A Lens-Pardo… - European Journal of …, 2024 - academic.oup.com
Objective Metabolic profiling is a valuable tool to characterize tumor biology but remains
largely unexplored in neuroendocrine tumors (NETs). Our aim was to comprehensively …
largely unexplored in neuroendocrine tumors (NETs). Our aim was to comprehensively …
Physiology of malate dehydrogenase and how dysregulation leads to disease
AD Parente, DE Bolland, KL Huisinga… - Essays in …, 2024 - portlandpress.com
Malate dehydrogenase (MDH) is pivotal in mammalian tissue metabolism, participating in
various pathways beyond its classical roles and highlighting its adaptability to cellular …
various pathways beyond its classical roles and highlighting its adaptability to cellular …
Animal and cell culture models of PPGLs–achievements and limitations
Research on rare tumors heavily relies on suitable models for basic and translational
research. Paragangliomas (PPGL) are rare neuroendocrine tumors (NET), developing from …
research. Paragangliomas (PPGL) are rare neuroendocrine tumors (NET), developing from …
Surgery for advanced adrenal malignant disease: recommendations based on European Society of Endocrine Surgeons consensus meeting
Methods A working group established by ESES reviewed the current guidelines and
undertook a literature search of the PubMed database focused on several clinical questions …
undertook a literature search of the PubMed database focused on several clinical questions …
Germline genetic variants in pheochromocytoma/paraganglioma: single-center experience
JV Lima, NM Scalissi, KC de Oliveira… - Endocrine …, 2023 - eo.bioscientifica.com
Pheochromocytoma and paragangliomas (PPGLs) are rare neuroendocrine tumors carrying
25–40% pathogenic germline gene variants (PGVs). We evaluated clinical, laboratory, and …
25–40% pathogenic germline gene variants (PGVs). We evaluated clinical, laboratory, and …