Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …

Background The oral route is the most popular route for the clinical administration of drugs to
treat various diseases. Before a drug is absorbed into the blood circulation, it must undergo …

This study was aimed at utilizing polysaccharides for the development of effective hydrogel
microparticles for oral insulin delivery that has a controlled, and sustained release to …

Lymph node metastasis is a frequent occurrence in a variety of tumour forms and poses an
enormous challenge to cancer treatment. This process is critical to the development of the …

The present research work was aimed to explore the ability of nanostructured lipid carriers
(NLCs) to improve oral bioavailability of Nintedanib esylate (NE) via lymphatic uptake. The …

Bioavailability assessment in the development phase of a drug product is vital to reveal the
disadvantageous properties of the substance and the possible technological interventions …

Liquid self-nanoemulsifying drug delivery system (L-SNEDDS) of curcumin and quercetin
were prepared by dissolving them in isotropic mixture of Labrafil M1944CS®, Capmul …

In this study, we sought to overcome the poor solubility and bioavailability of
bismethoxycurcumin (BDMC) by fabricating a BDMC-loaded self micro-emulsifying system …

Ursolic acid (UA), a pentacyclic triterpenoid, has gained attentions due to its various health-
promoting benefits, but exhibits poor bioavailability. This could be enhanced by changing …

Highlights The FTIR, DSC, and the XRD characterization confirmed the successful complex
formation between resveratrol and phospholipid. The optimal SEDDS formulation exhibited …