[HTML][HTML] Recent advances in targeted strategies for triple-negative breast cancer

S Zhu, Y Wu, B Song, M Yi, Y Yan, Q Mei… - Journal of Hematology & …, 2023 - Springer
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer,
negatively expresses estrogen receptor, progesterone receptor, and the human epidermal …

[HTML][HTML] Glucose metabolism and glucose transporters in breast cancer

E Shin, JS Koo - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Breast cancer is the most common malignancy in women worldwide and is associated with
high mortality rates despite the continuously advancing treatment strategies. Glucose is …

A MOF-based potent ferroptosis inducer for enhanced radiotherapy of triple negative breast cancer

L Zeng, S Ding, Y Cao, C Li, B Zhao, Z Ma, J Zhou… - ACS …, 2023 - ACS Publications
Radiotherapy (RT) is one of the important clinical treatments for local control of triple-
negative breast cancer (TNBC), but radioresistance still exists. Ferroptosis has been …

[HTML][HTML] Inhibition of glycolysis-driven immunosuppression with a nano-assembly enhances response to immune checkpoint blockade therapy in triple negative breast …

X Ren, Z Cheng, J He, X Yao, Y Liu, K Cai, M Li… - Nature …, 2023 - nature.com
Immune-checkpoint inhibitors (ICI) are promising modalities for treating triple negative
breast cancer (TNBC). However, hyperglycolysis, a hallmark of TNBC cells, may drive tumor …

Nano-ultrasonic contrast agent for chemoimmunotherapy of breast cancer by immune metabolism reprogramming and tumor autophagy

X Yang, M Zhao, Z Wu, C Chen, Y Zhang, L Wang… - ACS …, 2022 - ACS Publications
The functional status of innate immune cells is a considerable determinant of effective
antitumor immune response. However, the triple-negative breast cancer tumor …

[HTML][HTML] Emerging role of PARP inhibitors in metastatic triple negative breast cancer. Current scenario and future perspectives

G Barchiesi, M Roberto, M Verrico, P Vici… - Frontiers in …, 2021 - frontiersin.org
Triple negative tumors represent 15% of breast cancer and are characterized by the lack of
estrogen receptors, progesterone receptor, and HER2 amplification or overexpression …

[HTML][HTML] Prognostic significance and tumor immune microenvironment heterogenicity of m5C RNA methylation regulators in triple-negative breast cancer

Z Huang, J Pan, H Wang, X Du, Y Xu… - Frontiers in cell and …, 2021 - frontiersin.org
Purpose The m5C RNA methylation regulators are closely related to tumor proliferation,
occurrence, and metastasis. This study aimed to investigate the gene expression …

[HTML][HTML] Therapeutic progress and challenges for triple negative breast cancer: Targeted therapy and immunotherapy

R Yang, Y Li, H Wang, T Qin, X Yin, X Ma - Molecular biomedicine, 2022 - Springer
Triple negative breast cancer (TNBC) is a subtype of breast cancer, with estrogen receptor,
human epidermal growth factor receptor 2 and progesterone receptor negative. TNBC is …

Micellar paclitaxel boosts ICD and chemo-immunotherapy of metastatic triple negative breast cancer

X Qiu, Y Qu, B Guo, H Zheng, F Meng… - Journal of Controlled …, 2022 - Elsevier
Triple negative breast cancer (TNBC) with easy metastasis,“cold” tumor immune
microenvironment, and lack of targeted therapy remains poorly prognosed. Chemo …

[HTML][HTML] Co-delivery of gemcitabine and paclitaxel plus NanoCpG empowers chemoimmunotherapy of postoperative “cold” triple-negative breast cancer

B Guo, Y Qu, Y Sun, S Zhao, J Yuan, P Zhang… - Bioactive materials, 2023 - Elsevier
Triple-negative breast cancer (TNBC) due to lack of clear target and notorious “cold” tumor
microenvironment (TME) is one of the most intractable and lethal malignancies. Tuning …